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  • Relapse of Pneumococcal Pneumonia and Emergence of Quinolone Resistance

    Four patients treated with levofloxacin for pneumococcal pneumonia had one or more relapses with levofloxacin-resistant isolates. In 5 of 6 relapses, the infecting strain was identical to the initial levofloxacin-susceptible strain by DNA typing.
  • Clinical Briefs in Primary Care Supplement

  • Pharmacology Watch: Study Shows Oral IIb/IIIa Receptors Increase Mortality

    Another study has shown an increase in mortality associated with the use of an oral IIb/IIIa receptor antagonist.
  • UTI and Bacterial Pods: The Invasion of the Bladder Snatchers*

    Experiments suggest that bacteria may persist within bladder epithelial cells in a biofilm contained within pods, thus accounting for bacterial persistence manifested as chronic or recurrent urinary tract infection.
  • Linezolid Superior to Vancomycin?

    Randomized trial data suggest that linezolid is superior to vancomycin in the treatment of nosocomial MRSA pneumonia.
  • Updates

    Difficulties in Diagnosing Intestinal TB; Can Human Betaretroviruses Trigger Autoimmune Disease?; Rifampin and Pyrazinamide No Longer Recommended for Latent TB; Meningitis in Children with Cochlear Implants
  • Hospital Medicine: Past, Present, and Future

    Affecting virtually every aspect of our health care system, the stunning growth and rapid integration of hospital-based medicine has affected the practice of both medicine and surgery by significantly modifying the delivery of inpatient, outpatient, and subacute care. This article details the history of hospitalists in the United States by defining the practice of hospital medicine and reviewing the evidence extolling its virtues. Although hospital medicine appears here to stay, work must still be done to address a number of current and future issues facing hospitalists and the health care community embracing them.
  • Clinical Briefs in Primary Care Supplement

    Increase in Blood Glucose Concentration During Antihypertensive Treatment as a Predictor of Myocardial Infarction; Adverse Drug Events in Ambulatory Care; Prevention of Hip Fracture by External Hip Protectors; Rapid MRI vs Radiographs for Patients with Low Back Pain; Effectiveness of Anticholinergic Drugs Compared with Placebo in the Treatment of Overactive Bladder; A Randomized Trial of a Low Carbohydrate Diet for Obesity
  • Pharmacology Watch: Nasally Administered Flu Vaccine Comes to United States

    Nasally Administered Flu Vaccine Comes to United States; Paxil: Not Recommended for Children; Prilosec Granted OTC Status; Finasteride and Prostate Cancer; Xolair: First Biologic Agent for Asthma; West Nile Virus Update; Study Shows COX-2 Inhibitors Appear Safe with Aspirin in Asthma Patients; Lamictal Approved for Bipolar Disorder
  • Check Nortrel stock — Barr Labs issues recall

    If you have any patients who use 28-day packages of Nortrel 7/7/7 oral contraceptives (OCs), be sure your clinic has initiated its patient notification plan following the July 9, 2003, voluntary recall issued by the pills manufacturer, Barr Laboratories of Pomona, NY.