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  • Alcoholic Neuropathy is Not Due to Thiamine Deficiency

    Sixty-four patients with alcoholic neuropathy (ALN), comprising 36 without thiamine deficiency and 28 with thiamine deficiency (ALN-TD), were compared to 32 nonalcoholic, thiamine-deficiency neuropathy patients to establish whether clinical and pathological features were similar in the 2 groups and to determine how thiamine deficiency related to ALN.
  • Genetic Epilepsies: Focus on the ARX Locus

    Homeobox genes comprise a family of highly conserved genes responsible for developmental patterning by regulating expression of target genes in a temporal, spatial, and tissue-specific fashion.
  • Pharmacology Watch: Study Shows Oral IIb/IIIa Receptors Increase Mortality

    Another study has shown an increase in mortality associated with the use of an oral IIb/IIIa receptor antagonist.
  • Clinical Briefs in Primary Care Supplement

    Prognostic Value of ABPMs in patients with Treated Hypertension; Tazarotene Cream in the Treatment of Psoriasis; Antihyperglycemic Effect of Oolong Tea in Type 2 Diabetes; Metformin and Thiazolidinedione Use in Medicare Patients with Heart Failure; Alcohol Consumption Patterns and Biologic Markers of Glycemic Control; Azelaic Acid Gel as a New Treatment for Papulopustular Rosacea
  • Do Dopamine Agonists Slow Parkinson’s Disease?

    The non-ergot dopamine agonists ropinirole and pramipexole effectively ameliorate the cardinal motor features of idiopathic Parkinsons disease.
  • A Prospective Study of Unruptured Cerebral Aneurysms

    The present report from the International Study of Unruptured Intracranial Aneurysms is the largest prospective analysis of the risk of rupture of unruptured asymptomatic cerebral aneurysm.
  • IVIg Infusion May Be Complicated by Ischemic Stroke

    Intravenous immunoglobulin (IVIg) is an effective treatment for a wide range of autoimmune neurological disorders. IVIg is well tolerated in general but may rarely result in anaphylaxis and acute renal failure, as well as thromboembolic complications such as pulmonary embolism and stroke. These recent reports in Neurology highlight the potential vascular consequences of IVIg.
  • Doctor, I’m Dizzy!

    Differentiating central from peripheral causes of vertigo is a recurrent clinical challenge that behooves reinforcement.
  • Clinical Briefs in Primary Care

    Prognostic Value of ABPMs in patients with Treated Hypertension; Tazarotene Cream in the Treatment of Psoriasis; Antihyperglycemic Effect of Oolong Tea in Type 2 Diabetes; Metformin and Thiazolidinedione Use in Medicare Patients with Heart Failure; Alcohol Consumption Patterns and Biologic Markers of Glycemic Control; Azelaic Acid Gel as a New Treatment for Papulopustular Rosacea
  • Low Gradient Aortic Stenosis

    Since patients with low gradient aortic stenosis are at higher risk for surgical replacement, more information concerning whom to select for surgery is desirable. Monin and colleagues from 6 centers in France studied 136 symptomatic patients with aortic valve area < 1.0 cm2, low cardiac index and a mean aortic pressure gradient < 40 mm Hg.