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Corticosteroid use is associated with an increased risk of symptomatic pulmonary embolism. The greatest risk is in the first 30 days of use and increases with increasing steroid dose.
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Low MEWS score may be beneficial in identifying a subset of hospitalized patients unlikely to benefit from nocturnal vital sign monitoring.
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The toxicity of statins was increased in older adults who were coprescribed the CYP3A4 inhibitors clarithromycin or erythromycin.
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In a matched, retrospective cohort study, early use of daptomycin compared to vancomycin in MRSA bacteremia with vancomycin MICs > 1 µg/mL resulted in improved clinical outcomes, including less clinical failure at 30 days, lower mortality and less persistent bacteremia.
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Despite better compliance with hand hygiene and screening, use of isolation, and other techniques, ICUs remain notorious breeding grounds for hospital-acquired infections. A universal decolonization strategy reduces the total number of ICU bloodborne infections.
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Childhood fibromuscular dysplasia is a fairly distinct entity from the typical adult form, and the "string of beads" finding on angiography is relatively uncommon.
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Sera from patients with Bickerstaff brainstem encephalitis demonstrate the ability to disrupt the blood-brain barrier; sera from Miller Fisher syndrome do not.
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Patients presenting with tumefactive demyelinating lesions have MRI characteristics indistinguishable from a primary central nervous system tumor. Many patients go on to have relapsing-remitting disease and may have recurrence of tumefactive lesions.
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In this case-control study, the authors report that there is no difference in the prevalence of chronic cerebrospinal venous insufficiency in patients with multiple sclerosis vs non-multiple sclerosis participants.
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Clopidogrel Added to Aspirin Reduces Ischemic Stroke Risk after TIA or Minor Stroke; Women Are at Greater Risk of Dying from Stroke Than Men
