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Calcium supplementation in women; type 2 diabetes treatments and pancreatitis risk; treating chronic idiopathic urticaria; rivaroxaban and VTE; and FDA actions.
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Optimism is associated with a significantly healthier lipid profile than is present in less optimistic persons, possibly due to healthier behaviors and lower body mass indices, which are found with increased frequency in optimistic individuals.
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A new product has been approved for the urgent reversal of warfarin or other vitamin K antagonists anticoagulation in the setting of acute bleeding. This human plasma-derived product contains vitamin K-dependent coagulation Factors II, VII, IX, and X as well as antithrombotic Protein C and Protein S. It is heat-treated and viral filtered. Prothrombin complex concentrate (PCC) is manufactured by CSL Behring GmbH in Germany and marketed by CSL Behring LLC as Kcentra. The product has been licensed in Germany since 1996.
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Five days of steroid treatment was as effective as 14 days of treatment in preventing repeat exacerbations of COPD in patients presenting to the emergency department with COPD exacerbations.
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The injection of a dextrose solution in and around the knee (prolotherapy) is an alternative treatment for the pain of knee osteoarthritis. A randomized, controlled trial shows that prolotherapy is effective for long-term control of knee pain and improvement in knee function.
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A new technique of evaluating liquid-based Pap smears has been developed to identify confirmed disease-specific mutations in patients with uterine and ovarian cancers.
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A recent multicenter study has shown that restricted activity not only does not decrease the rate of preterm birth in nulliparous patients with cervical length < 3 cm, but it can actually double this risk.