Clinical Publication
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When the Aortic Annulus Is Small, Does TAVR Valve Type Matter?
In this propensity-matched analysis of transcatheter aortic valve replacement (TAVR) registry patients with small aortic annuli, the hemodynamic advantage of self-expanding TAVR valves was not associated with better clinical outcomes compared with balloon-expandable valves up to five years.
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More Daily Steps Lowers Cardiovascular Disease Risk Among Older Adults
Researchers reported that for every additional 500 steps per day, the risk for heart disease, heart failure, and stroke declined by 14% among adults age 70 years and older.
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Mediterranean Diet Pairs Well with Immune Checkpoint Blockade
The popular healthy diet boosted response to unique cancer therapy among patients with advanced melanoma.
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Vitamin D3, Omega-3, and Their Effects on Frailty in Older Patients
Data from a large, randomized trial that included 25,871 adults age 50 years or older indicated 2,000 daily units of vitamin D3 and 1 g daily of omega-3 fatty acid supplementation did not affect frailty.
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Multivitamin-Mineral Supplementation vs. Cocoa Extract for Cognition
This large, randomized trial followed participants for three years and determined that daily use of a cocoa supplement was not associated with cognitive enhancement in older adults, whereas a multivitamin supplement was associated with significant cognitive benefits.
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Asymptomatic with Inverted T Waves
The ECG in the figure is from a healthy young adult without symptoms. Clinicians recorded this tracing as part of the patient’s employment physical exam. Is the T wave inversion likely to be a normal variant?
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Daprodustat (Jesduvroq)
Daprodustat can be prescribed to treat anemia caused by chronic kidney disease in adults who have been receiving dialysis for at least four months.
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Does Surviving an ECMO Stay Put Patients at Greater Risk for Mental Health Problems?
Survivors of extracorporeal membrane oxygenation (ECMO) demonstrated a modest increase in risk of new mental health diagnoses after discharge vs. ICU survivors who do not undergo ECMO.
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Can a Blood-Based Test Serve as a Biomarker for Parkinson’s Disease?
The authors of this proof-of-concept study proposed that a noninvasive assay detecting pathology-associated α-synuclein extracted from blood may reveal a reliable biomarker for Parkinson’s disease.
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Cutting Total Calorie Intake Is More Effective for Weight Loss
Researchers found monitoring total caloric intake may be more effective for losing weight than intermittent fasting.