Cardiology
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Carotid Occlusion Rarely Develops from Asymptomatic Carotid Artery Stenosis
Recent study indicates that the risk of progression to carotid occlusion is well below the risk of carotid stenting or carotid endarterectomy.
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Utility of Non-traditional Risk Factors in Patients Ineligible for Statin Therapy
Adding additional risk factors not in the pooled risk equation to low-risk subjects identified a sub-group with an observed event rate > 7.5% who may warrant statin therapy.
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Effect of Modified Valsalva Maneuver for Emergency Treatment of Supraventricular Tachycardia
In patients presenting with supraventricular tachycardia, a modified Valsalva maneuver with leg elevation and supine positioning at the end of strain was demonstrated to be more effective than the standard Valsalva maneuver at restoring normal sinus rhythm.
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Ceftazidime-avibactam — Formulary Considerations
Ceftazidime-avibactam is a new beta-lactam/beta-lactamase inhibitor combination approved for the treatment of complicated intra-abdominal infections in combination with metronidazole, and complicated urinary tract infections, including pyelonephritis in patients with limited alternative treatment options.
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Idarucizumab Injection (Praxbind)
The FDA has approved the first reversal agent for a direct oral anticoagulant. Idarucizumab is a humanized monoclonal antibody fragment derived from an IgG1 isotype molecule. -
Optimal Beta-blocker Dose Post-MI
Beta-blocker therapy after acute myocardial infarction was retired as a hospital performance measure because its almost universal acceptance removed its discriminating value. However, it is well known that clinically used doses are significantly lower than those achieved in the randomized trials, establishing their mortality-reducing benefits.
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Can We Safely Discharge Patients on the Weekend?
ABSTRACT & COMMENTARY: The link between weekend discharge and 30- and 90-day readmission rates.
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Kirtan Kriya Meditation on Stress and Alzheimer’s Disease
This review article shows that meditation, particularly Kirtan Kriya, can mitigate the negative biochemical effects of stress.
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Emergency Department Visits Related to Dietary Supplements
A 10-year chart review of 63 nationally representative emergency departments reveals 3667 cases of adverse events related to dietary supplement use; these are estimated to represent 23,005 emergency department visits yearly. Characteristics of the visits are described and categorized.
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Echinacea-based Infusion Noninferior to Oseltamivir in Early Influenza Treatment
Echinacea Hotdrink was found to be as effective as oseltamivir as early treatment intervention of clinically diagnosed and lab-confirmed influenza virus infections and had fewer adverse effects.