Cardiology
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Spironolactone for Resistant Hypertension
Recent studies suggest spironolactone is the most efficacious fourth drug for patients with drug-resistant hypertension.
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Is Sodium Restriction Detrimental in Chronic Heart Failure?
Dietary sodium restriction may have a detrimental effect on outcome in patients with symptomatic chronic heart failure.
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Is Sodium Restriction Detrimental in Chronic Heart Failure?
In an observational study of outpatients with NYHA class II or III heart failure, dietary sodium restriction (< 2500 mg/day) was associated with increased risk of death or heart failure hospitalization.
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Fecal Microbiota Transplantation: Patients Need No Convincing
Relapsing and refractory Clostridium difficile infection has become a real challenge for clinicians and affected patients alike. Some patients wind up in a seemingly never-ending cycle of illness, gradual improvement, followed by a prolonged vancomycin taper, and eventual relapse.
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Blood Transfusion in Cardiac Disease Patients
An observational study confirms the hypothesis that ischemic heart disease patients may do better with higher hemoglobin levels as compared to ICU patients without heart disease.
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Early Chest CT Can Improve Treatment for Community-acquired Pneumonia
In patients with suspected community-acquired pneumonia, early chest CT significantly changed management decisions.
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The Opioids Just Keeping Coming
Most opioid prescriptions are continued after a patient overdoses accidentally. Those patients are also at risk for a recurrent overdose.
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Potatoes Increase Risk of Type 2 Diabetes Mellitus
Potato consumption, particularly in the form of French fries, is strongly correlated with the development of type 2 diabetes.
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Perils of High-dose Vitamin D Supplementation
Bischoff-Ferrari H, et al. Monthly high-dose vitamin D treatment for the prevention of functional decline. JAMA Intern Med 2016; doi:10.1001.
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Chinese Herbal Medicine for Esophageal Cancer
Although Chinese herbal medicine probably does not slow disease progression or improve survival in esophageal cancer patients, it may improve quality of life and reduce adverse effects of radiotherapy and chemotherapy.