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In heterozygous familial hypercholesterolemia patients, rosuvastatin produced significantly greater reductions in LDL cholesterol, increases in HDL cholesterol, beneficial changes in other lipid values, and achievement of NCEP cholesterol goals than observed with equivalent doses of atorvastatin, with a similar adverse event profile.
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Since the results of the Womens Health Initiative randomized trials, many fewer postmenopausal women are using estrogen to control hot flashes. Alternatives include progesterones, antidepressants in low doses, caffeine avoidance, exercise, phytoestrogens, and black cohosh.
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Oral rofecoxib (Vioxx) may have a role in controlling postoperative pain patients undergoing knee surgery.
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In patients with acute anterior myocardial infarction the significance of inferior ECG ST-segment elevation is unclear. Thus, investigators from the GUSTO-I angiographic and the GUSTO-IIb angioplasty substudies evaluated the 1046 patients with anterior ST elevation and divided them into 3 groups.
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Talreja and colleagues from the Mayo Clinic in Rochester, Minn, reviewed biopsy specimens and clinical features of 143 patients who had pericardiectomy for proven pericardial constriction.
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In this paper from 2 Italian centers, Pappone and colleagues report the results of a randomized trial of prophylactic catheter ablation in previously asymptomatic patients with Wolff-Parkinson-White syndrome.
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Antihypertensive Treatment and Measurement at Home or in the Physicians Office; Inactivated Intranasal Influenza Vaccine and the Risk of Bells Palsy; Topiramate for Migraine Prevention
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This brief, individual CBT intervention, developed specifically to alter hypochondriacal thinking and restructure hypochondriacal beliefs, appears to have significant beneficial long-term effects on the symptoms of hypochondriasis.
