This study, the Multicenter Automatic Defibrillator Implantation Trial Reduce Inappropriate Therapy (MADIT-RIT), was designed to test the hypothesis that programming implantable cardioverter-defibrillator (ICD) therapies with higher detection rates or delayed detection before initiation of therapy would decrease inappropriate shocks in ICD patients.
Zolpidem and risk of falls; AVR and anticoagulation; statins in cancer patients; and FDA actions.
As our population ages and outcomes from revascularization also improve, more elderly patients are being referred for coronary artery bypass graft surgery (CABG) and for percutaneous coronary intervention (PCI).
Angioedema is an infrequent, but serious, adverse event from drug therapy. Drugs that affect the renin-angiotensin-aldosterone system have been linked to angioedema, but the relative frequency of this complication with these drugs is poorly understood.