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The History Matters!
How would you interpret today’s 12-lead electrocardiogram and long lead V1 rhythm strip if the history was that of an older adult with known coronary disease? Would your interpretation change if, instead, the patient was a younger adult with a known history of severe congenital heart disease, having been operated on a number of times as a child?
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Paltusotine (Palsonify) Tablets
The U.S. Food and Drug Administration has approved paltusotine, the second oral (after octreotide), but first once-daily formulation for the treatment of acromegaly in adults.
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Recombinant Herpes Zoster Vaccine in a Medicare Population
Receipt of adjuvanted recombinant herpes zoster vaccine was effective in individuals older than 64 years of age and maintained its efficacy in immunocompromised individuals. Added benefit accrued from receipt of the second vaccine dose, even if its administration was delayed.
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COVID-19 Rebound: To Retreat or to Re-Treat
Re-treatment of non-immunocompromised patients with mild-moderate COVID-19 rebound with nirmatrelvir/ritonavir provided no significant benefit.
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Potential Benefit of Glyburide in Moderate-Volume Acute Ischemic Stroke
An exploratory analysis of the CHARM trial suggests intravenous glyburide may improve outcomes in large hemispheric stroke patients with infarct volumes < 125 mL, particularly alongside thrombectomy, reducing edema, mortality, and the need for decompressive surgery, and highlighting a potential neuroprotective role.
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Acupuncture to Treat Low Back Pain in Older Adults
A multisite, three-arm, parallel-group randomized clinical trial of older adults in the United States with chronic low back pain found improvement in both pain and disability with the addition of acupuncture treatment compared to usual medical care alone.
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HIV Prevention and Education Needed for Young, Female Populations in the U.S.
Human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) is no longer an epidemic in the United States, but some parts of the country and some populations still have high rates of the disease among young women.
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HPV Self-Test Kits Could Save Time for Clinicians
The Food and Drug Administration (FDA) approved two HPV self-collection tests on May 14, 2024. These allow people to collect their own vaginal samples for HPV testing in clinic settings.
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Study Examines Dobbs Decision Effects on Permanent Contraception Rates
A close look at data from hundreds of thousands of permanent contraception procedures from Jan. 1, 2019, through March 31, 2023, found an increase in permanent contraception procedure rates for both females and males after the U.S. Supreme Court decision in Dobbs v. Jackson Women’s Health Organization.
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People with Disabilities Face Sexual and Reproductive Health Challenges, Study Shows
New research finds that female adolescents and young adults with disabilities face a few additional sexual and reproductive health challenges when compared with the same population without disabilities.