Articles Tagged With: diagnosis
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Clinical and Genetic Reassessment of Patients with Presumed Hereditary Polyneuropathy
This is an observational, cross-sectional study of patients seen at a specialized neuromuscular center with a clinical diagnosis of hereditary polyneuropathy, without a previously identified genetic diagnosis. The goal of this study was to assess the combination of clinical reassessment with updated genetic testing, including whole genome sequencing. Reassessment improved the diagnostic clarification rate in these patients.
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Blood GFAP Measurements for Rapid Diagnosis of ICH
The early diagnosis of spontaneous intracerebral hemorrhage (ICH) is important to initiate rapid interventions, such as lowering blood pressure and reversing the effects of antithrombotic medications. Plasma assays of glial fibrillary acidic protein may become a useful tool for the prehospital diagnosis of ICH, but it needs further study before adoption in the clinical setting.
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Physicians Are Cautiously Optimistic About AI in Psychiatric Medicine
Physicians are optimistic about how artificial intelligence tools will affect psychiatric medicine in the long-term, a recent study found.
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Examining the Effectiveness of Using AI Tools in Practice
A controlled trial comparing physician diagnostic performance with and without artificial intelligence (AI) found no significant difference in accuracy, quality, or other metrics, although AI alone outperformed both groups.
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A microRNA Diagnostic Biomarker for ALS
A specific pattern of eight micro ribonucleic acids (microRNAs) has been shown to differentiate patients with amyotrophic lateral sclerosis (ALS) from those with primary lateral sclerosis, Parkinson’s disease, and healthy controls. It remains to be determined if these differences will continue throughout the course of the disease.
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Pediatric Pneumonia, Diagnostic Uncertainty, and Communication
Community-acquired pneumonia is a common cause of hospitalization among children in resourced countries and is the leading cause of childhood death in lower-income countries. However, the diagnosis of pneumonia is fraught with uncertainty, and management practices vary widely. Clinician behaviors and attributes that engender trust in the face of diagnostic uncertainty have been documented.
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Diagnostic Uncertainty in Community-Acquired Pneumonia
A national retrospective cohort study from the Veterans Administration found a high rate of diagnostic discordance for patients admitted and discharged for community-acquired pneumonia (CAP). Improvement in the diagnosis of CAP is needed.
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Recent Cases Add to Complexity of Treatment Withdrawal Decision-Making
Many ethics consults involve conflicts over withdrawal of life-sustaining treatment. If patients’ families are aware of recent cases demonstrating recovery potential in patients with traumatic brain injury who were thought to have a low chance of survival, it can make the decision-making process even more challenging.
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Another Step in the Journey to Combat Diagnostic Errors in Hospitalized Patients
Diagnostic errors in hospitalized patients who died or were transferred to the intensive care unit were common in this large retrospective, multicenter trial and frequently associated with patient harm. Problems with clinical assessment and ordering and interpreting tests were the most prevalent diagnostic process faults, with sepsis the diagnosis most associated with diagnostic error.
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Inappropriate Diagnosis of Pneumonia Is Common in Hospitalized Patients
A cohort study that included 48 hospitals in Michigan found that 12% of patients treated for community-acquired pneumonia were diagnosed inappropriately. Older age, dementia, and presenting with acute change in mental status increased the risk for misdiagnosis.