Articles Tagged With:
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Updates on Cervical Cancer Prevention: Summary and Projected Effect
HPV vaccination and updated screening strategies offer OB/GYN providers powerful tools to prevent cervical cancer. Recent advances, risk-based management, and enhanced follow-up can provide targeted care for high-risk patients to reduce the incidence of cervical cancer while avoiding unnecessary procedures.
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Postoperative Antibiotics After Cesarean Delivery to Reduce SSI
This randomized, double-blind clinical trial including 321 women with a pre-pregnancy body mass index > 30 kg/m2 demonstrated no difference in surgical site infection composite between participants receiving oral cephalexin and metronidazole for 48 hours after cesarean delivery compared to placebo (5.6% vs. 6.8%; odds ratio, 0.80; 95% confidence interval, 0.33-2.22; P = 0.64).
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Adverse Outcomes in Women with a History of Recurrent Pregnancy Loss
Women with a history of recurrent pregnancy loss are at significantly increased risk of adverse outcomes, including preeclampsia, placental abruption, cesarean delivery, preterm birth, stillbirth, and perinatal mortality.
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What Is the Genitourinary Syndrome of Lactation?
In this systematic review of 65 studies, the prevalence of vaginal atrophy among postpartum breastfeeding patients was 63.9% (95% confidence interval [CI], 55.3% to 71.6%) and vaginal dryness symptoms occurred in 53.6% (95% CI, 33.6% to 72.5%). Dyspareunia also was elevated, with a prevalence of 60.0% at three months, (95% CI, 45.1% to 73.3%), 39.7% at six months, (95% CI, 28.9% to 51.5%), and 28.5% at 12 months (95% CI, 26.3% to 30.9%).
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Contemporary Cardiovascular Disease Deaths in Asian Americans
An analysis of a Centers for Disease Control and Prevention database has shown the cardiovascular disease mortality rate is higher in Asian Americans than in non-Asian Americans and that this excess mortality is particularly prevalent in Filipino Americans.
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Surgery or Fibrinolysis for Thrombosed Mechanical Valves
A randomized trial of urgent surgery vs. thrombolytic therapy for symptomatic left-sided mechanical valve thrombosis has shown that surgery completely restores valve function in all patients compared to three-quarters of patients with thrombolytic therapy, but at a cost of higher in-hospital complications and mortality.
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Left Ventricular Size and Outcomes in Aortic Regurgitation
A multinational, retrospective, observational registry study of patients with significant aortic valve regurgitation has shown that left ventricular end-systolic dimension and volume measurements are valuable for risk-stratifying such patients and should be incorporated into the guidelines for when to intervene.
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SGLT2 Inhibitor Plus Aldosterone Antagonist for HFpEF: Safe? Efficacious?
A prospective, open-label, blinded outcome crossover trial of dapagliflozin plus spironolactone vs. dapagliflozin alone in patients with heart failure with preserved or mildly reduced left ventricular ejection fraction resulted in a greater reduction in natriuretic peptides, which was accompanied by a greater decline in kidney function and a rise in serum potassium.
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ApoB vs. Lp(a): Which Is More Important for CAD Risk?
In UK Biobank participants without known atherosclerotic cardiovascular disease or diabetes or taking lipid-lowering therapy, the risk of developing coronary artery disease is best determined by apolipoprotein B particle number, but elevated lipoprotein(a) adds significant risk, so both should be considered.
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Acute STEMI or Something Else?
Interpret the electrocardiogram (ECG) in the figure without the benefit of any clinical information. Is this ECG indicative of an acute anterior ST-elevation myocardial infarction?