Articles Tagged With:
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Managing Pediatric Diabetic Emergencies
Managing pediatric diabetic emergencies is challenging. Children, especially those younger than 2 years of age, may present with subtle symptoms. Diagnosis and management must be initiated intentionally and monitored carefully to optimize each child’s outcome. The authors provide an evidence-based approach to recognition, diagnosis, and management of diabetes in children.
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Outpatient Management of Patients with VTE Diagnosed in the ED
Many low-risk patients with venous thromboembolism diagnosed in the emergency department can safely be treated outside the hospital. Studies show that outpatient management achieves similar outcomes to inpatient care in terms of recurrence and bleeding, while improving convenience and reducing healthcare costs.
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Update on Pediatric Facial Trauma
Pediatric facial trauma is common, and clinicians require an understanding not only of common injury patterns, but also of recommended diagnostic strategies and evidence-based management approaches.
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Elamipretide Injection (Forzinity)
The U.S. Food and Drug Administration has granted accelerated approval to elamipretide, the first treatment for Barth syndrome — a life-threatening disease of the mitochondria. Elamipretide is a mitochondrial cardiolipin binder that improves mitochondrial structure and function.
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Psychiatric Medications and Long QT Syndrome: A Safe Combination?
A retrospective study of patients with electrocardiogram long QT interval syndrome and psychiatric disease suggests that with proper pharmacologic treatment and counseling, the patients can be treated safely with psychiatric drugs known to increase the QT interval.
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Measles Testing of Persons with HIV
A Dallas County human immunodeficiency virus clinic review from 2015-2025 found that only 11% of people with HIV had documented measles immunity, with younger patients, white and Hispanic patients, and patients with low CD4 counts more likely to be seronegative.
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Repeated Head Impacts Are Associated with Tau Astrogliopathy
This study demonstrates that both traumatic brain injury and participation in contact sports are independently associated with increased tau astrogliopathy, particularly thorn-shaped astrocytes, even when cases of chronic traumatic encephalopathy neuropathologic change are excluded.
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Efficacy of Adding Aspirin to OACs for CAD Patients
A randomized, placebo-controlled trial of adding aspirin to oral anticoagulant therapy in patients with chronic coronary artery disease at high risk of atherothrombotic complications and major bleeding was stopped early because aspirin increased the risk of all-cause mortality. In addition, aspirin was associated with an increase in atherothrombotic complications and major bleeding.
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Cycling into Cognitive Health: Lessons from the U.K. Biobank
In this large prospective study, active travel (especially cycling) was associated with lower dementia incidence both overall and for specific types of dementia as well as greater hippocampal volume.
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Detection of Atrial Fibrillation in Cryptogenic Stroke
The ANTARCTICA study is a pooled meta-analysis from multiple prospective studies of patients with ischemic stroke of varying etiologies, where loop monitoring was performed for atrial fibrillation detection. The groups were divided into cryptogenic stroke/transient ischemic attack or non-cryptogenic stroke/non-stroke. Both groups demonstrated an unadjusted rate of atrial fibrillation of about 30%.