Articles Tagged With: TBI
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Repeated Head Impacts Are Associated with Tau Astrogliopathy
This study demonstrates that both traumatic brain injury and participation in contact sports are independently associated with increased tau astrogliopathy, particularly thorn-shaped astrocytes, even when cases of chronic traumatic encephalopathy neuropathologic change are excluded.
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New Data Inform Decision-Making on Withdrawal of Life-Sustaining Therapy Timing
New research challenges assumptions about prognosis in severe traumatic brain injury cases, showing some patients recover well despite poor indicators. Ethicists emphasize caution and individualized decisions.
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Post-Traumatic Headaches: Common and Complicated
The brain’s ability to modulate pain influences the development and persistence of post-traumatic headache (PTH). Functional magnetic resonance imaging (fMRI) studies in people with PTH show higher pain-induced brain activation in specific regions, such as the postcentral gyrus, superior temporal gyrus, and ventral striatum, as compared to healthy controls. Over 16 weeks of observation, progressive normalization in pain-induced brain activation was seen in the PTH group with headache improvement, with persistently elevated activation in the non-improvement PTH group.
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Determinants of Long-Term Outcome After Concussion
This cohort study of U.S. veterans found that mild traumatic brain injuries occurring alongside psychological trauma are associated with long-term post-concussive symptoms and disability. The authors postulate that the traumatic context contributes to the development of post-traumatic stress disorder, which may in turn potentiate long-term sequelae.
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California Court Rules Nurse Lacks Qualifications as Expert Witness in TBI Case
The California Court of Appeal addressed the importance of expert witness qualifications in a medical malpractice case stemming from a wrongful death claim. The lawsuit was brought by the father of a young man in his 20s who experienced a severe traumatic brain injury after a motor vehicle accident. The father alleged that the hospital’s negligent treatment and failure to follow appropriate protocols during the patient’s care contributed to his son’s death.
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Examination and Imaging Correlates of Visual Symptoms in Mild TBI
This study highlights measurable visual and structural changes in patients with mild traumatic brain injury (mTBI). Findings include convergence insufficiency, reduced contrast sensitivity, and occipital cortex changes, despite normal standard imaging and visual field tests. Machine learning discerned mTBI from controls with 72% accuracy, suggesting advanced diagnostics can uncover subtle abnormalities.
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Is Autologous Bone Marrow Cell Therapy a Potential Treatment for Traumatic Brain Injury?
This study proposes that autologous bone marrow mononuclear intravenous infusion for severe traumatic brain injury in children appears safe and potentially may be efficacious.
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Lack of Brain Temperature Variation May Predict Mortality Among Patients with Brain Injury
Variations in brain temperature appear to be a normal physiological variable. An absence of brain temperature variation may be a novel predictor of mortality among patients with brain injury.
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Risk Factors and Outcomes for Post-Traumatic Seizures After Moderate to Severe Traumatic Brain Injury
Using data collected from an Australian registry, a population-based cohort study identified risk factors for early post-traumatic seizures (EPS), associated morbidity and mortality, and contribution to development of post-traumatic epilepsy (PTE). EPS were associated with significant in-hospital morbidity, poorer outcomes, and increased risk of mortality at 24 months of follow-up. Patients with EPS had a higher risk of developing PTE.
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Recovery of Consciousness After TBI: Who Recovers and When?
The majority of patients with moderate to severe traumatic brain injury who survive and are treated in acute rehabilitation centers will recover consciousness.