Articles Tagged With:
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Progressive Encephalomyelitis with Rigidity and Myoclonus with GlyR Antibodies
This is a retrospective observational study of patients with a clinical diagnosis of progressive encephalomyelitis with rigidity and myoclonus (PERM) and glycine receptor (GlyR) antibodies identified at a specialized neuroimmunology laboratory, as well as an accompanying systematic literature review. The goal of the study was to describe the clinical features and long-term outcome of patients with GlyR antibody-mediated PERM.
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Relationship Between Abnormal Amyloid-β Deposition and Regional Brain Atrophy on MRI
In a retrospective review of patients followed in the Wisconsin Alzheimer Disease Research Center, the time course of early deposition of amyloid-β correlated with regional atrophy in temporoparietal regions of interest independent of tau positivity.
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Home Training for Cerebellar Ataxias: A Randomized Clinical Trial
In this randomized clinical trial comparing home high-intensity aerobic training to home balance training among individuals with cerebellar ataxias, investigators found that home high-intensity aerobic training improved ataxia symptoms, fatigue, and aerobic fitness more than dose-matched home balance training.
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Elinzanetant Capsules (Lynkuet)
The U.S. Food and Drug Administration has approved elinzanetant, a second non-hormonal neurokinin receptor antagonist, following fezolinetant (Veozah), for the treatment of vasomotor symptoms associated with menopause. Elinzanetant is distributed by Bayer HealthCare Pharmaceuticals, Inc., as Lynkuet.
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Ambulatory Glucose Monitoring a Risk for Bloodborne Pathogens
A report of acute hepatitis B virus infection in a skilled nursing facility diabetes patient in North Carolina prompted an investigation for potential exposures and assessment of infection prevention practices in the facility.
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Fleas, Typhus, and Texas
Cases of flea-borne typhus are dramatically increasing in Texas.
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Detection of Atrial Fibrillation in Cryptogenic Stroke
The ANTARCTICA study is a pooled meta-analysis from multiple prospective studies of patients with ischemic stroke of varying etiologies, where loop monitoring was performed for atrial fibrillation detection. The groups were divided into cryptogenic stroke/transient ischemic attack or non-cryptogenic stroke/non-stroke. Both groups demonstrated an unadjusted rate of atrial fibrillation of about 30%.
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Spironolactone for the Treatment of Acne Vulgaris
In this meta-analysis of 563 patients from five randomized controlled trials, objective assessment of acne improvement was higher in the spironolactone group compared to the placebo group (odds ratio, 6.59; 95% confidence interval, 3.50-12.43).
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Early vs. Late Catheter Ablation for Atrial Fibrillation in Older Patients
An observational study from China in older patients with persistent atrial fibrillation (AF) has shown that an earlier diagnosis to catheter ablation time of ≤ 12 months compared to > 12 months is associated with lower rates of AF recurrence and adverse cardiovascular outcomes.
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Obtaining Pediatric Vascular Access
Vascular access is a cornerstone of effective pediatric emergency care and essential for resuscitation of critically ill or injured children. This review provides a comprehensive overview of pediatric vascular access strategies in the emergency department, emphasizing evidence-based methods and practical techniques to improve success rates and minimize complications.