Debate over the cardiovascular effects of COX-2 inhibitors has raged for more than a year since a special communication was published in JAMA last August suggesting an increase in cardiovascular events with rofecoxib (Vioxx). Now a large retrospect, the cohort study from the Tennessee Medicaid program seems to confirm the prothrombotic effects of rofecoxib, at least in high dose.
There are a number of significant advancements in pain management that will impact your clinical practice, including more frequent use of patient-controlled analgesia and increased use of conscious sedation.
The foot is divided into three anatomic regions: the forefoot, made up of the fourteen phalanges and the five metatarsals; the midfoot, made up of the navicular, the cuboid, and the three cuneiforms (the medial, the middle, and the lateral); and the hindfoot, made up the talus and calcaneus.
