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The authors provide evidence that vascular endothelial growth factor (VEGF)-receptor inhibitors by themselves can trigger a painful neuropathy and can aggravate paclitaxel-induced neuropathy in mice by interfering with the neuroprotective effects of VEGF.
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Stroke Incidence May Be Increasing in Younger People; Cancer May Be a Risk Factor for Ischemic Stroke; Physical Exercise Reduces White Matter Lesion Burden and Brain Atrophy in the Elderly; Serious Cardiac Arrhythmias May Occur During First 72 Hours After Stroke
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Fatal headaches are associated with age over 50, loss of consciousness and collapse, and worst/thunderclap character of the headache.
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Abnormal movements, outside of seizure and ataxia, are an uncommon chief complaint among children presenting to the emergency department. A working knowledge of movement disorder phenomenology, etiology, differential diagnosis, and associated potentially life-threatening conditions is essential for emergency physicians. Each movement disorder and its clinical considerations will be discussed in detail in the article.
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People understand that natural disasters like floods, hurricanes, or tornadoes are going to happen every year. That's why EDs across the country routinely conduct practice drills so that they have plans in place to deal with mass-casualty events.
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Noting that opioid analgesics are among the drugs most often associated with adverse drug events, the Joint Commission has issued a Sentinel Alert, urging hospitals to step up their efforts to prevent complications and deaths from use of these powerful drugs.
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While the Centers for Disease Control (CDC) in Atlanta has been calling on EDs to routinely test patients for HIV since 2006, the practice is hardly widespread.
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Coughs and hiccups are common emergency department complaints. While the majority of their causes are benign, patients with these symptoms can suffer from significant distress and impaired quality of life. Most patients with these symptoms can be effectively managed by understanding the pathophysiology and differential diagnosis of these symptoms and by using evidence-based therapy. It is important for the physician to be aware of the emergent conditions that may present with these seemingly benign complaints.
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