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Articles

  • Male Hypogonadism

    Testosterone replacement therapy is a growing industry that deserves discussion between patients and their healthcare providers. Recently, many insights into new formulations, advertising, and potential risks have heightened the controversy surrounding low testosterone syndrome, appropriate diagnosis, and risks and benefits of testosterone supplementation. A plethora of non-regulated supplements termed “testosterone boosters” are being marketed directly to the public without adequate assessment. Therefore, it is important for healthcare providers to be familiar with how to conduct and interpret diagnostic tests as well as with appropriate use of TRT as established by various medical organizations, including the Endocrine Society. This review will discuss the definitions, pathophysiology, causes, clinical manifestations, appropriate diagnostic testing procedures, and the role of testosterone supplementation with currently available formulations, with special attention to efficacy and adverse effects in hypogonadism in men.

  • Alzheimer’s Disease: What the Primary Care Physician Needs to Know

    This article explores current medical approaches to Alzheimer’s dementia, the most common subtype of the known dementias or neurocognitive disorders. Preventive treatment is at the forefront of efforts to defeat this progressively impairing disorder; but to be effective, intervention must start well before symptoms begin. The role of the primary care provider in initiating vigorous and early preventive measures and applying appropriate pharmacologic and non-pharmacologic interventions at each stage of disease progression is reviewed and discussed.

  • Pharmacologic Management of Type 2 Diabetes Mellitus: Part 2

    This two-part series of articles will address pharmacological agents, except insulin, used to manage type 2 diabetes mellitus. Part 1 covered sodium glucose co-transporter-2 inhibitors, incretin-based therapies, amylin analog, and dopamine receptor agonists. Part 2 will focus on biguanides, thiazolidinediones, sulfonylureas, meglitinides, alpha-glucosidase inhibitors, and bile acid resins, as well as the authors’ treatment recommendations. Appendix A (http://bit.ly/2eyB4Px) is a comprehensive table of the effectiveness and costs of various combination therapies.

  • Managing Type 2 Diabetes Mellitus: Part 1

    MONOGRAPH: Covering sodium glucose co-transporter-2 inhibitors, incretin-based therapies, amylin analog, and dopamine receptor agonists.

  • Acute Knee Pain

    Many nontraumatic conditions affect the knee and can cause severe impairment and morbidity to patients. However, primary care physicians should feel comfortable in addressing and treating acute knee pain.

  • Rosacea: Pathophysiology, Clinical Features, and Treatment

    MONOGRAPH: Here's an in-depth guide for the primary care physician.

  • Arterial Ischemic Stroke Prevention and Risk Factor Management

    MONOGRAPH: Here is the best evidence-based practice for stroke diagnosis, prevention, and risk factor management.

  • Current Management of Abscesses

    Abscesses are common skin and soft tissue infections, and their incidence has continued to rise substantially over the years. Despite the high prevalence of abscesses in current care, the management of abscesses varies widely between care providers. This article reviews the current management options for simple cutaneous abscesses in patients, including review of the epidemiology, differential diagnosis, diagnostic studies, and changing practice of wound cultures and antibiotic therapy. In addition, this article outlines the essential steps of abscess management, informing practitioners of current best practice options as evidenced by current literature or expert opinion.

  • Meningitis Update

    MONOGRAPH: Meningitis is inflammation of the meninges lining the brain that if allowed to progress ultimately leads to increased intracranial pressure.

  • Treatment of Acute Ischemic Stroke

    MONOGRAPH: The faster definitive stroke treatment is administered, the better the outcomes. Unfortunately, most patients arrive too late.