Primary Care/Hospitalist
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Pilocarpine Hydrochloride Ophthalmic Solution 1.25% (Vuity)
Pilocarpine ophthalmic solution (OS) can be prescribed to treat presbyopia.
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Intensive Monitoring for Asymptomatic Atrial Fibrillation Did Not Prevent Strokes
Screening with an implantable loop recorder resulted in dramatically higher rates of atrial fibrillation detection and ensuing anticoagulation, but without a significant decrease in risk of stroke or systemic embolism by six years of follow-up.
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Importance of Age in the Application of Coronary Artery Calcium Detection
Using coronary CT strategy as a diagnostic first line in patients with symptoms suggestive of coronary artery obstruction revealed relying on the coronary calcium score alone is inadequate for younger patients with a higher frequency of non-calcified obstructions.
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Reduce the Risk of Autoimmune Disease with Vitamin D, n-3 Fatty Acid Supplements
A randomized, controlled trial that included older adults showed vitamin D3 2,000 units daily or n-3 fatty acids 1,000 mg daily over five years reduced the incidence of autoimmune diseases 25% to 30%.
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Looking Back, COVID-19 Vaccination Woes Were Predictable
Efficacy, protection duration, side effects, and FDA approval factored into decisions about choosing a COVID-19 vaccine.
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Fluvoxamine Reduces the Risk for Hospitalization from COVID-19
Researchers found fluvoxamine (100 mg twice a day for 10 days) lowered the risk for hospitalization among high-risk outpatients diagnosed with COVID-19.
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Is This Wellens’ Syndrome?
The ECG in the figure is from a young adult man known to have a bicuspid aortic valve. He presented to the ED following a presyncopal episode. The patient has not experienced chest pain recently. Does this patient have Wellens’ syndrome?
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Varenicline Nasal Spray (Tyrvaya)
Varenicline nasal spray is indicated to treat the signs and symptoms of dry eye disease.
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Intensive Blood Pressure Lowering Does Not Affect Small Vessel Disease Progression
Intensive blood pressure lowering was not associated with worsening but did not demonstrate any benefit in this population over standard blood pressure management.
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Environmental Shedding of MRSA Far Greater Than From Multidrug-Resistant Gram-Negative Bacilli
An observational cohort study showed shedding of methicillin-resistant Staphylococcus aureus by colonized patients outside hospital rooms or during outpatient clinic visits occurred more often than in those colonized by multidrug-resistant gram-negative bacilli.