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In a neonatal intensive care unit in Arizona, five infants and ten health care providers were found to have pertussis during a two month period.
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This study comes from the legacy Multicenter AIDS Cohort Study (MACS) of almost 7000 men who have sex with men, both HIV-infected and non-HIV, for 3 decades.
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On March 21, 2014, two new antibiotics with activity against methicillin-resistant Staphylococcus aureus (MRSA) each received unanimous recommendations from FDA Advisory Committees for approval for treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by Gram-positive organisms.
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The recent publication of the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) and the continuing introduction of new psychoactive drugs create challenges for updated diagnostic and therapeutic choices for primary care patients.
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Group A streptococcus (GAS) may cause disease both by direct infection, termed suppurative disease, and also by the response of the body to an antecedent infection, termed nonsuppurative disease. An invasive GAS infection is defined as one in which GAS can be isolated from a part of the body that is normally sterile, as would be the case in pneumonia but not in pharyngitis.
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Since the introduction of the vaccine against H. influenzae, there has been a significant decrease in the number of children presenting with epiglottitis. Although there is little evidence that the disease has increased in adults, clearly the percentage of cases in adults compared to children has increased. Further, there is greater recognition of milder cases with direct visualization and imaging.
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Nationally, nonblack children with otitis media more frequently receive broad-spectrum antibiotics than black children do. The majority of children with otitis media in the United States receive inappropriate treatment with broad-spectrum antibiotics.
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Meningitis is very unlikely in otherwise healthy-appearing febrile infants older than 21 days of age. Thus, cerebrospinal fluid analysis might not be needed as part of a “routine” evaluation of these babies.
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In the fifth and sixth decades of the 20th century, Charles Smith reported the results of skin testing with coccidioidin, a culture filtrate of the mycelial phase of Coccidioides.
