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In this issue: Calcium supplementation in women; type 2 diabetes treatments and pancreatitis risk; treating chronic idiopathic urticaria; rivaroxaban and VTE; and FDA actions.
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Although the levonorgestrel intrauterine system (LNG IUS) has been shown to be an effective treatment for heavy menstrual bleeding (HMB), previous clinical trials included rigorous criteria focused primarily on measuring the severity of bleeding.
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During the past few months, there has been a pleth-ora of articles published with important clinical implications, and I have found it difficult to pick just one to review.
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LAP2 was a phase 3 clinical trial to assess the non-inferiority of laparoscopy compared with laparotomy for recurrence of uterine cancer after surgical staging.
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Ninety-six women with breast cancer undergoing radiotherapy during a 5- to 6-week interval were randomized to either a qigong group or a wait-list control group. The results indicate that the women in the qigong group had clinically significantly less depressive symptoms and better quality of life than the control group.
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In patients with hepatitis C, having already been treated (unsuccessfully) with interferon, three times daily silymarin in two doses (both supratherapeutic) did not change serum ALT after 24 weeks.
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Grapefruit is a popular fruit worldwide because it is tasty, nutritious, and increasingly viewed as healthy. The original grapefruit was white and very seedy, but varieties have been selected to give seedless and more red cultivars.1
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This large, prospective, cohort trial followed women for 10 years using validated food questionnaires to assess if the consumption of walnuts, other tree nuts, and peanuts was associated with the incidence of the development of type 2 diabetes.
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Asthma is the most common chronic pediatric respiratory disease and remains one of the most common reasons children in the United States require hospitalization. Acute exacerbations of asthma can be life-threatening. While most of these acute exacerbations can be managed successfully in the office or in the emergency department, a few children with severe exacerbations may require admission to the intensive care unit.
