Browse Obstetrics/Gynecology Articles by Topic

Does Topiramate Decrease the Efficacy of Oral Contraceptives?

Women taking low-dose topiramate (< 200 mg per day) and oral contraception did not experience more contraceptive failures compared to women taking other headache remedies (propranolol, metoprolol, amitriptyline, venlafaxine, or verapamil).

Identifying and Testing BRCA Gene Variant Carriers Meeting NCCN Criteria

A large percentage of patients who meet criteria for breast cancer gene (BRCA) testing based on family history do not have it completed until after a personal cancer diagnosis, thus missing the opportunity for risk-reducing strategies.

Surgical Management of Missed and Incomplete Abortion: Is Hysteroscopy Useful?

In this randomized controlled trial of 563 women comparing vacuum aspiration and operative hysteroscopy for incomplete spontaneous abortion, there was no difference in pregnancy rates within the following two years (62.8% hysteroscopy vs. 67.6% vacuum aspiration; risk difference, -4.8%; 95% confidence interval, -13% to 3%).

Menstrual Suppression Method Outcomes Among Transgender and Gender-Diverse Adolescents

In a retrospective chart review of transgender and gender-diverse adolescents at a single institution seeking menstrual suppression methods, most individuals had high rates of method continuation, amenorrhea, improved bleeding, and a reduction in dysphoria and mood symptoms.

Azithromycin Prophylaxis for the Prevention of Maternal Sepsis or Death in Women Undergoing Vaginal Delivery

A single oral dose of azithromycin dramatically reduced the risk of maternal sepsis or death among women planning vaginal deliveries compared to placebo but had little effect on neonatal sepsis or mortality.

Identifying High-Risk Cancer Patients Through Appropriate Screening

Less than 20% of average-risk women receive guideline-adherent cervical cancer screening, and guideline-adherent screening was highest for primary HPV testing.

OB/GYN Clinical Alert Celebrates 40 Years

Does Topiramate Decrease the Efficacy of Oral Contraceptives?

In this retrospective cohort study, women taking low-dose topiramate (< 200 mg per day) and oral contraception did not have more contraceptive failures compared to women taking other headache remedies (propanolol, metoprolol, amitriptyline, venlafaxine, or verapamil), with an adjusted rate difference of 0.00 (95% confidence interval, -0.3, 0.3).

CIN2 Is More Likely to Progress if HPV 16 Is Present

This study examined rates of cervical intraepithelial neoplasia grade 2 (CIN2) regression and progression among women ages 25-30 years and found that regression rates varied by human papillomavirus (HPV) genotype: 51% regression and 47% progression in HPV 16 infections compared to 83% regression and 16% progression for infections with other HPV types.

Diagnosis of Obstructive Sleep Apnea During Pregnancy

Obstructive sleep apnea is associated with several adverse maternal and fetal outcomes.