Obstetrics/Gynecology
RSSArticles
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Finding New Clinical Activity in Endometrial Cancer from Optimizing Molecular Pathways
Everolimus, combined with letrozole, produced unexpected clinical activity in a cohort of previously treated recurrent endometrial cancer patients.
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HPV screening: Option to cytology-based options
Primary human papillomavirus (HPV) screening can be considered as an alternative to current U.S. cytology-based cervical cancer screening methods, according to new interim guidance from the Society of Gynecologic Oncology and the American Society for Colposcopy and Cervical Pathology.1
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Data reaffirm the effectiveness of LNG, copper intrauterine devices
Findings from a recent analysis of data from a large, multi-country study of women using levonorgestrel or copper intrauterine devices (IUDs) indicate that while both forms of contraception have high levels of efficacy, the levonorgestrel device daily releasing 20 mcg (Mirena LNG IUD, Bayer Healthcare Pharmaceuticals, Wayne, NJ) was associated with a significantly lower risk of pregnancy, including ectopic pregnancy, than copper IUDs.1
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New HPV vaccine covers 9 types of HPV
Get ready to include a new human papillomavirus (HPV) vaccine at your facility. The Food and Drug Administration (FDA) has approved Gardasil 9 from Kenilworth, NJ-based Merck Sharp & Dohme Corp., a subsidiary of Merck & Co.
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Some groups continue to bear disproportionate burden of STIs
While the latest national surveillance data show signs of progress in reducing chlamydia and gonorrhea among young people ages 15-24, the numbers and rates of reported cases of these two diseases continue to be highest in this group compared to other age groups.1
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Research focuses on health implications tied to PCOS
Women diagnosed with polycystic ovary syndrome (PCOS) face an elevated risk of developing heart disease, diabetes, mental health conditions, reproductive disorders, and cancer of the lining of the uterus. -
More emphasis needed on vaccination for HPV — What is your approach?
A new analysis of national data indicates about half of girls in the United States receive the human papillomavirus (HPV) vaccine at the recommended age. -
Remind all women about importance of folic acid
While fortifying grain foods with the B vitamin folic acid has saved about 1,300 babies every year from being born with serious birth defects of the brain and spine known as neural tube defects (NTDs), women of reproductive age still should be counseled to take a multivitamin with folic acid every day. -
Scientists eye impact of expedited partner therapy
Results of a public health intervention promoting the use of free expedited partner therapy (EPT) indicate it substantially increased use of the medicine and might have cut rates of chlamydia and gonorrhea infection. -
Endometrial Protection: Which Progestogen Is Best?
After a lost decade, increasing numbers of women and providers are recognizing the benefits of postmenopausal hormonal therapy. For women with an intact uterus, endometrial protection is required when systemic estrogen therapy is used. Since activity at the glucocorticoid and androgen receptor may lead to adverse health effects in some women, use of pure progesterone receptor agonists may offer advantages. However, the use of natural progesterone is problematic due to low potency and poor bioavailability with oral dosing. Local therapy with the levonorgestrel intrauterine device (off-label) may be an excellent choice for many women.