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Blumenthal and colleagues point out in the introduction that psychological factors are recognized to play a significant and independent role in the development of ischemic heart disease and its complications, but it is not clear if psychological or behavioral interventions will reverse established cardiac conditions. They undertook the present study to test the hypothesis that stress reduction would lead to better cardiovascular health in individuals with established ischemic heart disease.
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In 1985 5.6% of pregnant patients were 35 years of age or older, and in 2002 that figure rose to 12.5%. It is estimated that last year 20% of the pregnant population was older than 34 years of age.
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Is Holding NSAIDs Prior to Surgery Rational?; Low-Dose Aspirin: Men vs Women; FDA Actions
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The rationale for this study is interesting. As the trial investigators point out, oxidative injury has been implicated as a key mechanism, leading to atherosclerotic cardiovascular disease and cancer.
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Given the widely variant survival characteristics of women with advanced ovarian cancer, discrete quantifiable differences in tumor biology must exist. Heretofore, accurate characterization has been elusive.
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Bath and gray from the division of stroke Medicine in the Queens Medical Centre, University of Nottingham, performed a meta-analysis of the published literature regarding the association between postmenopausal hormone therapy and risk of stroke.
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Choudhry and colleagues sought to establish the relationship between quality of care with clinical experience by reviewing 62 articles that measured physician knowledge or quality of care as well as time since medical school graduation or age.
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A rigorous operative and pathologic protocol for RRSO increases the detection rate of occult ovarian malignancy in BRCA mutation carriers nearly seven-fold. If confirmed, this finding will alter postoperative management because additional staging, chemotherapy, and follow-up may be necessary in affected women.
