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The Osteoporosis Prevention and Arterial Effects of tiboLone (OPAL) study was a 3-year, randomized, double-blind trial in 6 US centers and 5 European centers, treating 866 postmenopausal women with either 2.5 mg tiboLone daily, 0.625/2.5 mg daily of conjugated estrogens/medroxyprogesterone acetate, or placebo.
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The Lynch Syndrome (hereditary non-polyposis colorectal cancer) is a cancer susceptibility syndrome highlighted by early age onset of cancers of the colon and rectum, endometrium, ovary, small bowel, ureter and renal pelvis. It is mediated via autosomal dominant transmission of germ-line mutations in DNA-mismatch repair genes.
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Long-Term Effects of Warfarin Use; Statins Multiple Benefits; FDA Actions
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A medline search was conducted for comparisons of vaginal hysterectomy in patients with/without previous cesarean delivery. As might be anticipated, the studies were heterogeneous. For example, in one study, some cases had laparoscopic assistance.
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The authors sought to determine the relationship between psychiatric and sexual status of premenopausal women with fibromyalgia compared to a control group of healthy women.
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The purported advantages of the tension-free vaginal tape obturator (TVT-O) procedure include avoidance of bowel damage, reduction in risk of bladder and major vessel damage, and elimination of the need for routine cystoscopic evaluation during insertion.
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The therapeutic role of lymphadenectomy in patients with endometrial cancer is controversial and challenging to study given the relative infrequency of metastatic disease and the generally good prognosis of newly diagnosed patients. Nevertheless, prior work in limited sized cohorts has suggested that the number of nodes resected may be prognostic and informative in planning subsequent adjuvant treatment.
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This study was made possible by the mayo Clinic Cohort Study of Oophorectomy and Aging, the main aim of which is to detect new cases of age-related diseases, especially Parkinson's disease and dementia. This report focused on the mortality outcomes.
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In the vast majority of hospitals magnesium sulfate has been the drug of choice to stop labor in patients presenting with preterm contractions.
