OB/GYN Clinical Alert
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What Are Your Patients ‘Hearing’ About Menopausal Hormonal Therapy?
Data from the prospective Nurses’ Health Study demonstrate a weak association between menopause onset after age 50 years and use of hormone therapy and hearing loss. The most likely explanation is “noise.”
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Genital HPV in Men: How Common Is It?
In this U.S. cross-sectional survey, the prevalence of genital human papillomavirus (HPV) infection in adult men was 45%, of which 25% were high-risk subtypes. The overall rate of HPV vaccination among those who were eligible was 11%.
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Don’t Forget About Functional Hypothalamic Amenorrhea
Functional hypothalamic amenorrhea is a common but often overlooked cause of menstrual dysfunction that remains a diagnosis of exclusion.
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Maternal Mortality, Postpartum Hemorrhage, and Tranexamic Acid: The WOMAN Study
A multicenter study involving patients in 193 countries has shown a decrease in maternal mortality in women with postpartum hemorrhage who were given tranexamic acid once the diagnosis was made.
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Obesity and Endometrial Cancer
Obesity is a major risk factor for endometrial cancer as well as for other major comorbidities.
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Oral Contraceptives and Quality of Life
In this three-month randomized, double-blind trial comparing oral contraceptives to placebo, the authors found a small decrease in general well-being scores but no effect on depressive symptoms. The short time period and small effect size introduce doubt into the validity of these findings.
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Contraindications to Home Birth
A new study of neonatal death rates over a four-year period in the United States has identified two new contraindications to home birth.
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Pelvic Floor Changes in First Pregnancy: How Do They Affect Quality of Life?
Nulliparous women experience worsening urinary incontinence, fecal incontinence, and perineal pain in pregnancy. Urinary incontinence symptoms are associated with a negative effect on quality of life.
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Hot Flashes: A Marker of Increased Cardiovascular Risk?
Among otherwise healthy midlife women, the presence of frequent hot flashes was associated with impaired endothelial function, a risk factor for cardiovascular disease.
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Abortion for Fetal Anomalies: Trends in Gestational Age
In this retrospective cohort study, the median gestational age at the time of abortion for fetal aneuploidy decreased from 19 weeks in 2004 to 14 weeks in 2014. However, the gestational age at the time of abortion for fetal structural abnormalities remained at ≥ 20 weeks over the study period.