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Smith and colleagues performed a case-control study of venous thrombosis and hormone users in postmenopausal women registered in a large health maintenance organization (the Group Health Cooperative) in the state of Washington.
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The Infection Risk of Acid-Suppressing Drugs; Is Rosuvastatin As Safe As Other Statins?; Which Estrogen Preparation is the Safest?; FDA Actions.
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In working up vaginitis symptoms, useful signs are inflammation and odor, information concerning odor and itching are useful symptoms, and office microscopy is the most accurate laboratory test.
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In a recent study from Japan, Toivonen and colleagues set out to determine how much more susceptible women experiencing placental abruption were to having a recurrence of this problem in a subsequent pregnancy. They scanned a database which encompassed 14,326 deliveries during a one-year period at a busy university hospital.
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Over the last few decades, technology has existed to evaluate the cytotoxic effects of single-agent and combination chemotherapy on cancer cell lines derived from an individual patient's tumor specimens. However, investigators and clinicians have been frustrated as the fruit of this technologya reliable and reproducible assay to help them treat their patients with the agent or agents most likely to benefit themhas yet to be proven.
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A very simple study appeared in the August edition of the American Journal of Obstetrics and Gynecology. It dealt with the ability of clinicians to precisely determine the position of the fetal head in the maternal pelvis during the second stage of labor.
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Although safer than traditional colonoscopy, virtual colonoscopys lower sensitivity and efficacy coupled with the increased cost would rule against recommending this procedure at the current time.
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In a prospective, multicenter study, Cristofanilli and colleagues tested 177 patients with clinically detectable metastatic breast cancer for levels of circulating tumor cells both before and after the initiation of various forms of therapy. The response to therapy was followed using standard clinical detection, but blood samples were also collected to determine the burden of tumor cells in the circulation.
