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To assess the efficacy and toxicity of combination pegylated liposomal doxorubicin (PLD) and carboplatin against industry-standard paclitaxel and carboplatin, patients with histologically proven ovarian cancer with recurrence more than 6 months after first- or second-line platinum- and taxane-based therapies were randomly assigned by stratified blocks to CD (carboplatin area under the curve [AUC] 5 plus PLD 30 mg/m2) every 4 weeks or CP (carboplatin AUC 5 plus paclitaxel 175 mg/m2) every 3 weeks for at least 6 cycles.
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Learn to be more specific in your sexual health history taking. Results of a new study from the Kinsey Institute for Research in Sex, Gender and Reproduction at Indiana University in Bloomington indicate that no uniform consensus exists when the term "had sex" is used.
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This is a small U.S.-based clinical trial of 23 adolescent women (ages 14-18) randomized to levonorgestrel-releasing vs Copper T intrauterine device (IUD).
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The management of a patient with suspected fetal macrosomia remains an enigma. Not being able to come up with a consistent plan of management for macrosomia is compounded by our inability to reliably predict it.
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Depot medroxyprogesterone acetate (DMPA) is a highly effective progestin-only contraceptive that is widely used by adolescents. DMPA is also associated with suppression of ovarian production of estradiol, and with a decrease in bone density in some users.
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The primary objective of this retrospective study was to estimate the incidence of genetic counseling referral for ovarian cancer patients who were at high risk for carrying a mutation in BRCA1 or BRCA2.
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In this issue: Fractures and bisphosphonate therapy, warfarin anticoagulation and influenza vaccine and cotrimoxazole, antiplatelet therapy with clopidogrel and aspirin, FDA Actions.
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To investigate the relation between dietary fat intake and the risk of endometriosis, these authors analyzed 12 years of prospective data from the Nurses' Health Study II that began in 1989.