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Early experience with fetal MMC repair suggests a decreased need for ventriculoperitoneal shunting, arrest, or slowing of progressive ventriculomegaly, and consistent resolution of hindbrain herniation.
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Menstrual irregularities are arguably the mainstay of gynecologic office practice. The differential diagnosis for this common presentation is quite extensive, but a common cause is reduced central hypothalamic GnRH drive due to lifestyle issues.
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The FDA has approved Pfizer's eplerenone (Inspra) for the treatment of congestive heart failure (CHF) in patients who have sustained a myocardial infarction.
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Despite guidelines presented by several organizations, significant numbers of women with ovarian cancer are not being provided with appropriate care.
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In an intent-to-treat analysis, the use of conjugated equine estrogen combined with continuous medroxyprogesterone acetate by menopausal women increased the hazard ratio of invasive breast cancer to 1.24.
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The data in this case-control study of combined estrogen plus progestin therapy revealed an increased risk of breast cancer, particularly invasive lobular tumor, regardless of whether the progestin component was taken sequentially or continuously.
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Birth weight discordancy of > 15% for same sex and > 30% for different sex confer greatest risk of adverse perinatal outcomes in the absence of abruption.
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Following radiation therapy, adjuvant extrafascial hysterectomy decreased the risk of relapse for patients with bulky stage IB cervical cancer without improving survival.
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The vasomotor flush is viewed as the hallmark of the female climacteric, experienced to some degree by most postmenopausal women. In the Massachusetts Womens Health Study, the incidence of hot flushes increased from 10% during the premenopausal period to about 50% just after cessation of menses.
