Nutrition
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MIND Matters: Diet, Exercise, and Engagement in Cognitive Health
This multicenter, randomized clinical trial showed that a highly structured, multidomain lifestyle intervention modestly but significantly was associated with improved global cognitive function throughout two years in at-risk older adults, compared to a lower-intensity, self-guided program.
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Can Vitamin D Supplementation Slow Cellular Aging?
In a large randomized, double-blind, placebo-controlled trial, vitamin D3 supplementation modestly but significantly slowed the rate of leukocyte telomere shortening over four years.
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Weight Loss Without Bone Loss: Mediterranean Diet and Exercise in Older Women
This systematic review found that, among older women undergoing intentional weight loss, bone density is better preserved with a calorie-restricted Mediterranean diet combined with physical activity, compared to a standard Mediterranean diet alone.
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Exploring the Benefits of Time-Restricted Eating and Nutritional Counseling
In a randomized trial, adding time-restricted eating (limiting eating to an eight- to 10-hour window) to standard nutritional counseling improved hemoglobin A1c, glycemic control, and other markers of cardiometabolic health when compared to standard treatment alone.
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Eat Your Fruits and Veggies to Decrease HPV Infection
Data from a large-scale national health and nutrition survey from 2003-2016 were used to examine the risk of genital human papillomavirus infection in 10,543 women ages 18-59 years.
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Is It Past Time to Change Dietary Guidelines for Alcohol Use?
Analysis reveals that previous studies demonstrating the health benefits of moderate alcohol drinking were of low quality and that the relatively few published studies meeting the minimal quality criteria to avoid this problem do not show significantly lower mortality risk for moderate alcohol drinkers.
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CVD Risk from Ketogenic Diets
A recent analysis of the UK Biobank data found that subjects on a low-carbohydrate, high-fat diet had higher levels of low-density lipoprotein cholesterol and apolipoprotein B, and an increase in incident major adverse cardiovascular events over a 12-year follow-up than subjects on a standard diet.
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Is Weight Loss the Key to Heart Health?
The second trial of semaglutide in obese patients with heart failure and preserved left ventricular ejection fraction, this one in people with type 2 diabetes, also has shown significant improvements in symptoms and exercise function with significantly fewer adverse effects than placebo-treated patients.
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Does Calcium Intake Cause Cardiovascular Disease?
A large population study of calcium intake at dinner vs. breakfast showed an increased risk of heart disease.
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Lifestyle Interventions and HbA1c in Prediabetic Patients
A comprehensive analysis of medical records shows that referral of patients with prediabetic risk factors to an intensive lifestyle change program results in significant improvements in critical cardiovascular risk factors, including hemoglobin A1c levels and obesity; these changes are more pronounced in men than in women.