Neurology
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Antibiotics for Traveler’s Diarrhea
International travel carries a risk of colonization by antimicrobial-resistant intestinal flora. Using quinolone, but not a macrolide, during travel further increases the risk of acquisition of extended-spectrum, beta-lactamase-producing Enterobacteriaceae.
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The Effect of Age on Cholesterol-Lowering Therapy
Investigators analyzed data on the effect of age on cardiovascular (CV) outcomes and LDL cholesterol-lowering by alirocumab vs. placebo in recent acute coronary syndrome patients. They found alirocumab can lower the rate of CV events regardless of age — and produce more absolute benefit with age.
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Healthcare Personnel COVID-19 Hospitalizations and Vaccine Prioritization
During the period of study, 5.9% of individuals hospitalized for COVID-19-related reasons were healthcare providers (HCP), with approximately one-third involving HCP who were not expected to directly contact patients.
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Managing Appendicitis Medically
A multicenter, randomized trial showed that 10 days of antibiotics results in comparable outcomes as surgery. Three in 10 patients treated with antibiotics required surgery within 90 days.
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Even Moderate COVID-19 Cases Can Cause Serious Neurological Problems
Strokes, seizures, and movement disorders just a few complications observed.
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Artificial Intelligence Coming to EDs to Improve Stroke Diagnosis
Strokes, especially posterior circulation events, are associated with significant diagnostic error in the ED. Machine learning models can be designed to capture subtle signs and assist providers in catching cases that might otherwise go undetected.
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Is There Bundle Branch Block?
Try to interpret the ECG in the figure without the benefit of any clinical information. What do you see?
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Bamlanivimab Injection
Bamlanivimab is a neutralizing recombinant IgG1 monoclonal antibody that connects to the receptor-binding domain of the spike protein of SARS-CoV-2. The drug blocks attachment and entry of the virus into human cells.
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When Aortic Stenosis Is Almost Severe: What Happens Next?
A study of patients with normal flow, low gradients, normal left ventricular systolic function but with calculated aortic valve areas <1.0 cm2 showed that about half of them progressed to severe aortic stenosis during the 25-month median follow-up period.
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Rifampin vs. Isoniazid for Latent Tuberculosis
A health system cost comparison showed that four months of rifampin was safer and less expensive than nine months of isoniazid in high-income countries, medium-income countries, and African countries.