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Proteomics: A New Method to Understand the Influence of Genetic Variation on Disease Pathogenesis

The combination of genome-wide association studies with the analysis of messenger ribonucleic acid and unique proteins in the brain, cerebrospinal fluid, and plasma can shed new light on our understanding of the genetic risks for the development of various neurological diseases.

What Is Focal CIDP?

Chronic inflammatory demyelinating polyneuropathy (CIDP) usually is diagnosed in patients who have a generalized disorder. However, there are focal syndromes that have been observed and diagnosed under different names that meet many of the clinical and electrodiagnostic criteria of CIDP and may be referred to as “focal” CIDP.

MRI Changes and Functional Outcomes Among Adults with Severe HSV Encephalitis

Herpes simplex virus is a common cause of encephalitis worldwide. When treated promptly, the mortality rate decreases from 70% to 15%, but many patients remain disabled. This multicenter cohort study analyzed magnetic resonance imaging in patients diagnosed with herpes simplex encephalitis admitted to the intensive care unit to identify factors associated with poor outcome at 90 days.

Researchers Find Lower Amyloid Levels in Patients on Blood Sugar Control Drug

An investigation reveals an interesting trait among those taking a common diabetes management solution.

Finerenone Tablets (Kerendia)

Finerenone can be prescribed to lower the risk of sustained estimated glomerular filtration rate decline, cardiovascular death, non-fatal myocardial infarction, end-stage kidney disease, and hospitalization from heart failure in adults with chronic kidney disease associated with type 2 diabetes.

Association of Sleepwalking and REM Sleep Behavior Disorder in Men with Parkinson’s

In this retrospective, cross-sectional study of men, both sleepwalking and rapid eye movement sleep behavior disorder were associated with the development of Parkinson’s disease.

Anticholinergic Use for Three Months or More Increases Dementia Risk

There is a significant increase in dementia risk associated with the use of anticholinergic medications for three months or longer.

A Probiotic May Cause Sepsis and Death

Saccharomyces boulardii is a probiotic yeast that may cause fungemia and other fungal infections.

Common Herbal and Dietary Supplements for Patients with Type 2 Diabetes: Part 2

The authors review chromium, cinnamon, fenugreek, garlic, and Gymnema sylvestre as complementary and alternative medicine supplements for managing type 2 diabetes.

Is AV Block Complete?

The dual lead rhythm strip in the figure was obtained from an elderly patient with syncope. Is there AV dissociation? Is there complete AV block? This is a challenging tracing because a different diagnosis is suggested by the first five beats in the rhythm strip, compared to the last four beats.