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In this prospective study of older ICU patients (mean age, 67 years), frailty as assessed by a simple scale was present in one-third and was strongly associated with increased risk of adverse events, morbidity, and mortality.
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In this large observational study in four hospitals with a standardized rapid response system, among patients with an initial team activation who were not immediately transferred to the ICU, those with one or more additional activations during the hospitalization were more likely to need ICU care and had both longer hospital stays and higher mortality.
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Hospital-based infection surveillance experts nationwide participated in a survey to access the level of agreement in diagnosing ventilator-associated pneumonia by evaluating six identical case studies. The level of agreement between participants was poor.
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This pilot study reports that dexmedetomidine might be the sedative of choice for less ill mechanically ventilated ICU patients who take antidepressant medications at home.
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The recent publication of the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) and the continuing introduction of new psychoactive drugs create challenges for updated diagnostic and therapeutic choices for primary care patients.
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What is the Best Treatment for Cerebral Cavernous Malformations?
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In this prospective study, the authors use brain imaging criteria to determine whether acute febrile status results in acute hippocampal injury and potentially chronic hippocampal sclerosis.
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A new case-control study finds that increased levels of dichlorodiphenyldichloroethylene (DDE), which is the metabolite of the pesticide dichlorodiphenyltrichloroethane (DDT), are associated with an increased risk for Alzheimer's disease.
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Trochlear headaches should be considered in patients with new onset, constant, unilateral eye pain, especially when the pain is aggravated by eye movement.