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Insulin Resistance at the Blood-Brain Barrier in Alzheimer’s Disease

Alterations in cerebrovascular insulin receptor isoform levels were associated with Alzheimer’s disease pathology and caused deficits in insulin signaling at the level of the blood-brain barrier.

Bone Density as a Dementia Risk Indicator

Researchers found some associations between bone density loss and a higher risk of developing dementia.

Self-Treatment of Recurrent Benign Paroxysmal Positional Vertigo

Using a cell phone-based app, self-treatment of recurrent benign positional paroxysmal vertigo was feasible and effective in most patients.

Healthy Lifestyle Behaviors Linked to Slower Memory Decline

In a population-based, prospective cohort study of 29,000 Chinese adults, researchers found healthy lifestyle was associated with slower memory decline, even in the presence of the apolipoprotein E4 allele.

Controlling Blood Pressure During Pregnancy Could Lower Dementia Risk

Investigators found an association between high blood pressure during pregnancy and a higher likelihood of developing dementia later in life.

Can a Blood-Based Test Serve as a Biomarker for Parkinson’s Disease?

The authors of this proof-of-concept study proposed that a noninvasive assay detecting pathology-associated α-synuclein extracted from blood may reveal a reliable biomarker for Parkinson’s disease.

Do Spinal Cord Stimulators Really Help for Chronic Pain?

The results of a comprehensive analysis of a large clinical database regarding treatment of patients with chronic low back pain did not support the benefit of spinal cord stimulators compared to conventional medical management for chronic pain.

Magnetic Brain Stimulation for Alzheimer’s Disease

Transcranial magnetic stimulation, targeted at the precuneus to help maintain a normal default mode network, shows some promise in slowing cognitive decline and maintaining normal electrophysiology in patients with mild to moderate Alzheimer’s disease.

Cumulative Estrogen Exposure Linked to Lower Stroke Risk

These findings could help clinicians sustain their postmenopausal patients’ neurological health.

Lecanemab-irmb Injection (Leqembi)

Lecanemab can be prescribed to treat Alzheimer's disease. Initiate this treatment in patients with mild cognitive impairment or mild dementia stage of disease, with confirmation of amyloid beta pathology.