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Platelet function testing identifies patients who do not respond to antiplatelet therapy and are at increased risk for acute stent thrombosis after neurointerventional procedures.
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The Babinski sign continues to be a valid bed-side test for pyramidal tract lesions.
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The anti-angiogenic monoclonal antibody, bevacizumab, shows great promise in the treatment of malignant gliomas.
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Some women with DVT may stop warfarin after six months; Vytorin and cancer; preventing recurrent stroke; and FDA news.
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A patient with primary, medically refractory dystonia, without a fixed skeletal deformity is a good candidate for pallidal deep brain stimulation. Shorter disease duration predicts a good outcome, but age of dystonia onset, severity of the disease, DYT1 status, and phasic/tonic predominance do not provide predictive value.
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Patients with transient global amnesia (TGA), with or without DWI+ (positive diffusion weighted images) on MRI, do not have an increase in any vascular risk factors compared to healthy age and sex matched controls.
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While about one-half of patients with migraine with aura have a patent foramen ovale, their right-to-left cardiac shunt does not increase the risk of white matter lesions on MRI scan of the brain.
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Patients with a history of migraine headaches are likely to have a headache in association with an acute ischemic stroke. The headaches are migraine-like and often occur with brainstem infarcts.
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This case review of 960 patients details the clinical features of musicians' hand dystonia, a potentially disabling focal task-specific dystonia often beginning at peak-career. Cases were predominantly male, with onset typically in the fourth decade and most commonly affecting the third digit or contiguous fingers on the ulnar side.
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Enzyme replacement therapy appears safe and effective for this rare genetic muscle disease.
