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CLIPPERS is a recently described steroid- responsive neurological syndrome manifested by subacute progressive cerebellar and brainstem inflammation with characteristic MRI appearance.
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Excessive daytime sleepiness appears to be an important risk factor for stroke. It is unknown whether this is related to obstructive sleep apnea or other mechanisms.
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This study shows improvement in visual acuity in some patients with steroid-unresponsive optic neuritis, but it is not clear if plasma exchange accounts for this improvement.
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Response to treatment of unilateral lumbar radiculopathy can be predicted by an abnormal needle EMG in the appropriate root distribution.
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Spreading depolarisations following severe traumatic brain injury are associated with a poor outcome. They serve to cause secondary injury and energy imbalance. This mechanism might provide a target for therapeutic intervention.
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Based on a retrospective study of 34 patients, the authors report that clinical manifestations of brain involvement are not uncommon in the neuromyelitis optica spectrum of disorders.
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New indication for rivaroxaban; new study on warfarin testing; medications causing adverse drug events; niacin as an add-on therapy; and FDA actions.
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Dihydroergotamine, in a longer 5-day intravenous protocol for refractory primary headache appears to be efficacious, but this older medication needs to be compared directly to newer migraine treatments.
