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Up to 50% of patients with seronegative ocular myasthenia gravis have antibodies to clustered acetylcholine receptor antibodies that can fix complement and passively transfer disease to experimental mice.
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Dementia and benzodiazepines; effectiveness of omega-3 fatty acid and Ginkgo biloba supplements; and FDA actions.
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Early seizures and EEG abnormalities as well as status epilepticus predicts worse outcome in SCN1A-positve Dravet syndrome in this new, large cohort of patients.
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Two recently reported Phase 3 trials for BG-12 demonstrated efficacy and safety in the treatment of relapsing-remitting multiple sclerosis.
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A Simple Score Can Predict Outcome after Ischemic Stroke; Mismatch Between Perfusion and Diffusion on MRI Can Identify Good Candidates for Endovascular Reperfusion Therapy; Cerebral Microbleeds May Be Associated with Elevated Vascular Endothelial Growth Factor
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Behçet's disease, while rare in North America, should be considered when appropriate, in light of the extensive travel and immigration patterns around the world.
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Thrombolysis for Ischemic Stroke Associated with Cervical Artery Dissection Does Not Improve Overall Outcome; In Patients with Lacunar Strokes, Addition of Clopidogrel to Aspirin Does Not Reduce Risk of Recurrent Stroke; Risk of Restenosis After Carotid Artery Stenting and Carotid Endarterectomy Are Similar
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Intravenous erythropoietin therapy appears to reduce retina nerve fiber layer thinning 16 weeks after onset of optic neuritis, but larger studies needed to detect differences in visual outcome.
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Biomarkers in the cerebrospinal fluid open the possibility of diagnosing early or even presymptomatic cases of Alzheimer's disease, thereby expanding the potential window for therapy.
