Internal Medicine
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Fluvoxamine Reduces the Risk for Hospitalization from COVID-19
A randomized, placebo-controlled trial found fluvoxamine (100 mg twice a day for 10 days) reduced the risk for hospitalization among high-risk outpatients diagnosed with COVID-19.
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Melioidosis in the United States
Four cases of melioidosis in four states occurred and at least one was traced to a contaminated commercial aromatherapy product.
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Pediatric Pneumonia — Diagnostic and Therapeutic Stewardship
A randomized, multicentered trial in the United Kingdom and Ireland showed children receiving amoxicillin for community-acquired pneumonia perform similarly well with lower dose (35-50 mg/kg/day vs. 75-90 mg/kg/day) and shorter duration (three vs. seven days) treatments.
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Surviving Sepsis 2021 Update
Some of the important changes include clearer differentiation of sepsis vs. septic shock and, for numerous recommendations, changing the strength and quality of evidence to support many.
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Coffee Consumption and the Curious Effects on the Heart
Real-time patient monitoring allowed researchers to observe a strange mix of short-term harms and benefits.
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Plant-Based Diets and Menopausal Hot Flashes
In this clinical trial, women randomized to a low-fat, vegan diet including one-half cup of cooked whole soybeans daily experienced a reduction in total hot flashes of 79% compared to 49% in the control group over 12 weeks of observation.
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Children and Electronics: A Longitudinal Study
This Finnish investigation of electronic media (e-media) use in young children revealed 95% of 5-year-olds studied exceeded guidelines for time spent with e-media. The authors noted an association between more screen time and additional psychosocial symptoms at 5 years old and found these associations were less prominent when measuring use of electronic games alone.
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Fish Consumption, Omega-3 Fatty Acids, and Cardiovascular Disease
Is there enough scientific evidence to suggest there are associations between fish consumption and risk of cardiovascular disease, or of mortality, among people who consume fish compared to those who do not consume fish?
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NIH Awards Grant for Psychedelic-Related Investigation
First federal investment in decades indicates evolving attitudes on this area of research.
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Medicare Sepsis Performance Measure Criteria Do Not Improve Outcomes
A longitudinal study of a single health system’s adherence to and outcomes of Medicare Sepsis Performance Measures (SEP-1) did not show an improvement in mortality despite improvements in adherence to guideline-mandated care.