Internal Medicine
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Birth Hospital ZIP Code and Neonatal Outcomes in Very Preterm Birth
This work may serve as a reminder to the healthcare provider of the importance of developing a complete and nuanced understanding of a patient and recognizing that environment often affects healthcare risk factors and wellness efforts.
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Intravenous Immunoglobulin for Stable CIDP: Stop or Taper?
First-line therapy for chronic inflammatory demyelinating polyneuropathy is intravenous immunoglobulin (IVIG), but the timing and method for withdrawal of this treatment are uncertain. In a retrospective review of stable patients on IVIG, investigators at the National Hospital in London observed that there was no significant difference in the likelihood of deterioration or response to retreatment if IVIG was stopped abruptly or tapered slowly.
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Neuropathological Findings in the Brains of Patients Who Died from COVID-19
In an autopsy study of 41 patients who died from COVID-19 in a single medical center in New York City, most of the brain pathology was the result of hypoxic-ischemic injury, infarction, and hemorrhage, with microglial activation and neuronophagia caused by inflammation. Studies for the presence of viral proteins were negative, and very low levels of viral ribonucleic acid were detected.
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Thalamic Stroke and Sleep Impairment: An Experiment of Nature
In a detailed clinical and electrophysiological study of sleep patterns in 12 patients with thalamic stroke, comparing them with 11 patients who had extrathalamic stroke, the investigators identified a marked decrease in slow wave sleep activity in the group with thalamic stroke. The clinical significance of this finding is uncertain but may have an effect on daytime cognitive performance.
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Biden to Send Military Aid to Struggling Hospitals, Millions of COVID-19 Tests to American Homes
The White House has announced its plan to respond to the omicron variant ahead of a possible winter case surge.
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AAP Recommends Routine HIV Screening, Prevention for All Teens, At-Risk Youth
The organization advises pediatricians to create safe spaces that allow frank discussions of sensitive topics.
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Analysts Suggest U.S. COVID-19 Vaccination Program Prevented Millions of Hospitalizations, Deaths
The pandemic has taken a heavy toll, but the damage could be so much worse without vaccines.
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Beyond COVID, Other Key Research Breakthroughs Occurred in 2021
American Heart Association highlights progress on diabetes treatment, stroke prevention, and anti-clotting medication.
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Infectious Disease Alert Updates
Candida auris Outbreak in Southern California; Healthcare Worker Vaccine Mandates
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Infections Before Age 20 Years Increase the Risk of Multiple Sclerosis
The relationship between childhood infections and the risk of multiple sclerosis is supported by mounting evidence. Using the Swedish Total Population Register, researchers found patients diagnosed with infection in adolescence showed a higher risk of multiple sclerosis, even after exclusion of infectious mononucleosis, pneumonia, and central nervous system infection.