Internal Medicine
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Rifampin and Prosthetic Joint Infections
In patients with prosthetic joint infection, no modifiable surgical or antibiotic factors were independently associated with success or failure. Factors not associated with outcomes include the extent of debridement, exchange of mobile parts, use of rifampin or of ciprofloxacin, and duration of intravenous or oral antibiotic administration.
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Delaying Antibiotics in Patients with Suspected Infection Increases Risk of Septic Shock
A retrospective cohort study found that delaying the first dose of antibiotics in patients suspected of having an infection in the emergency department led to a higher risk of progressing to septic shock and in-hospital mortality. Every hour antibiotics were delayed increased the risk of septic shock by 4%.
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Pregnant, Influenza-Infected, and Hospitalized
Almost one-third of women ages 15-44 years hospitalized with influenza were pregnant and almost 5% required intensive care.
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Modernizing Care of Children with Otitis Media
Otitis media usually resolves spontaneously. Antibiotics should not routinely be administered to children with acute uncomplicated otitis media.
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Prophylactic Post-Extubation Noninvasive Ventilation May Benefit Select Obese Patients
In this post hoc analysis, the use of noninvasive ventilation alternating with high-flow nasal cannula post-extubation decreased the risk of reintubation and death in obese and overweight patients at high risk for reintubation.
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Management of Right Ventricular Failure in the Critically Ill
This review will outline the management of right ventricular failure in the critically ill. -
Prevalence of Acute Myocarditis Related to COVID-19 Vaccination and SARS-CoV-2
Acute myocarditis is a diagnosis that has had a significant rise in prevalence and is the center of many recent discussions in the medical literature. Much of this recent increase has been secondary to SARS-CoV-2 and the COVID-19 vaccines. Amid the global SARS-CoV-2 pandemic, acute myocarditis has become much more prevalent in patients where it was previously a rare pathology. As a result of this outbreak, it has become a disease entity necessitating new and ever evolving clinical guidelines.
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Exploring the Cardio-Oncology Frontier
Investigators found a new cancer diagnosis was independently associated with a higher risk for cardiovascular death and nonfatal morbidity.
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Neurologists Add Nuance to Palliative Care Definition
Position paper authors underscore the importance of care goals discussions with patients and families throughout the disease course, not just at end of life.
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Report: Anxiety, Depression Up Significantly Among U.S. Children 2016-2020
Even before the onset of the COVID-19 pandemic, mental health conditions among Americans age 3 to 17 years were trending negatively.