Browse Internal Medicine Articles by Topic

Integrative Approaches to Alzheimer’s Disease

The medical community had warning. “Dementia in the Elderly: The Silent Epidemic,” a 1982 Annals of Internal Medicine landmark article, looked at the “greying of America” and noted one natural consequence of longer life span would be an explosive impact on the prevalence of dementia. Indeed, the epidemic has come — not only in the United States, but also globally, with dementia affecting an estimated 46 million people worldwide in 2015 and projected to affect 131 million by 2050.

Mind Over (Back Pain) Matter: An RCT

Mindfulness meditation training led to greater short-term function and less pain in adults with chronic low back pain when compared to a control group receiving only educational sessions.

Prenatal Exercise for Pregnancy-induced Hypertension and Weight Gain

Regular exercise throughout pregnancy wards off hypertension and excessive gestational weight gain without increasing the incidence of low birthweight infants.

A Brief Report of Clinical Trials Results from the 2016 International Stroke Conference

This article provides an overview of the research presented at the 2016 International Stroke Conference.

Hypoxia-induced Migraine

Hypoxia-induced migraine attacks with and without aura, in an experimental paradigm, were accompanied by dilation of cranial arteries in individuals who have migraine with aura, as well as in healthy control subjects.

Predicting Seizure Recurrence with Routine EEG after First Unprovoked Seizure

The authors systematically reviewed prospective and retrospective studies of adults and children undergoing routine electroencephalography (EEG) after a first unprovoked seizure who were followed for at least 1 year. Using positive likelihood ratios, an adult and child with epileptiform discharges on EEG were estimated to have a 77% and 66% probability, respectively, of recurrent seizures.

Pick Disease: Picking Away at the Pathology

The neuropathologic changes of Pick disease may sequentially progress through the brain in specified phases over time and may correlate with the progression of clinical symptoms.

Thalamic Pain: Who Is Likely to Develop This Disorder?

In a careful anatomic and physiologic study of patients with thalamic stroke, the authors demonstrated that the combination of anterior pulvinar nucleus involvement with spinothalamic dysfunction predicts a “thalamic pain syndrome” with > 90% sensitivity.

Peripheral Nerve Disorders After Cardiac Surgery

Following cardiac surgery, about 6% of patients will suffer a peripheral nerve injury, mostly due to compression, traction, or nerve ischemia. Proper patient positioning can prevent most of these injuries.

Treatment of Acute Ischemic Stroke

MONOGRAPH: The faster definitive stroke treatment is administered, the better the outcomes. Unfortunately, most patients arrive too late.