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Selecting Patients for Statin Primary Prevention

The new vascular disease risk calculator discriminates who will experience a vascular event in the near future better than using a trial entry criteria approach or a hybrid approach.

Is Anticoagulant Bridging Needed in Patients with Atrial Fibrillation Going to Surgery?

In patients with atrial fibrillation who had warfarin treatment interrupted for an elective operation or other elective invasive procedure, forgoing bridging anticoagulation was not inferior to perioperative bridging with low molecular weight heparin for the prevention of arterial thromboembolism and decreased the risk of major bleeding.

Infectious Disease Alert Updates

TB in Captive Elephants in the United States; TB Skin Testing and IGRA: An Ongoing Source of Confusion; LASIK, Humidifiers, and Mycobacterium chelonae Ocular Infections

Improve Treatment for Community-acquired Pneumonia

In patients with suspected community-acquired pneumonia, early chest CT significantly changed management decisions.

Saccharomyces Cerevisiae var boulardii ( S. boulardii ) and Antibiotic-associated Diarrhea

Saccharomyces boulardii administration failed to prevent antibiotic-associated diarrhea in a large randomized trial.

Antibiotic Use in Treatment of Children with Uncomplicated Severe Acute Malnutrition

Universal antibiotic use in the community-based treatment of uncomplicated severe acute malnutrition in children likely is not necessary in regions where suitable access to healthcare facilities is available.

Pediatric Coccidioidomycosis in California, 2000-2012

The incidence of pediatric coccidioidomycosis in California has increased significantly from 2000 until 2012, along with hospitalization for complicated disease. Latino children were most commonly infected, but African-American children were significantly more likely to be hospitalized.

Trimethoprim-sulfamethoxazole versus Placebo for Skin Abscesses After Incision and Drainage

A multicenter, double-blind, randomized clinical trial found that a 7-day course of trimethoprim-sulfamethoxazole following incision and drainage (I&D) resulted in a higher rate of cure for skin abscesses compared to I&D and placebo (80.5% vs 73.6%, respectively; P = 0.005).

The Current Outlook for Cardiac Tamponade

In the modern era, cardiac tamponade is most commonly caused by malignancies with poor prognosis. As compared to older literature, iatrogenic causes have increased, most resulting from complications of percutaneous coronary intervention.

Ventricular Tachycardia Ablation for Recurrent Arrhythmia and Coronary Artery Disease

Acute and long-term success rates with ventricular tachycardia ablation in patients with coronary artery disease are relatively high with an acceptably low complication rate.