Internal Medicine
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Pre-existing Health Determines Quality of Life, Physical Symptoms After ICU Discharge
The authors of this nested cohort study within a randomized, controlled trial of ICU survivors requiring > 48 hours of mechanical ventilation found that pre-existing comorbidity was the main determinant of long-term health-related quality of life.
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Massive Transfusion Protocols: Recommendations Regarding Initiation and Termination
This was a narrative review of societal recommendations for initiation of massive transfusion protocols based on objective scoring systems and clinical assessment and criteria for termination of protocols.
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Implementing Restrictive Transfusion Strategies to Improve Patient Outcomes
There is extensive evidence supporting a restrictive transfusion approach in critically ill patients and cardiac surgery patients. The data favor restrictive strategies in hip and knee surgery, except in geriatric patients for whom evidence favors a more liberal transfusion strategy. Evidence is sparse in sepsis, oncology, and acute coronary syndrome patients, warranting further study.
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Anything Other Than RBBB?
The ECG in the figure was obtained from a 60-year-old woman who presented to the ED with new-onset chest pain. The initial emergency care provider interpreted this tracing as showing complete right bundle branch block. Do you agree?
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Clinical Briefs
In this section: treating COPD with statins, tackling hearing loss with greater urgency, and educating patients about malignant melanomas. -
Insulin Lispro Injection (Admelog)
Admelog is indicated to improve glycemic control in adults and pediatric patients ≥ 3 years of age with type 1 diabetes mellitus and adults with type 2 diabetes mellitus.
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Clostridium difficile Recurrence by Orally Administered Fecal Microbiota Transplantation
Fecal microbiota transplantation orally administered in capsules was non-inferior to administration by colonoscopy.
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Blockade of CGRP for Migraine Prevention: Promising, but Not a Cure
Blockade of calcitonin gene-related peptide in patients with chronic or episodic migraine results in the prevention of about two headache days a month compared to placebo.
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Obesity Is a Hormonal Illness
Once obese, a patient’s metabolism adapts with insulin resistance to maintain body fat. High insulin levels promote fat storage and block fat burning.
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NOTICE: February 2018 was the final issue of this publication.
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