Internal Medicine
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Medical Cannabis and Chronic Pain
The authors of this systematic review investigating the effects of medical cannabis (MC) on chronic pain in adults found that there is limited evidence to support the use of MC in treating neuropathic pain and that there is insufficient evidence that MC improves other types of chronic pain.
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Mediterranean Diet and Frailty Risk
The authors of a review and meta-analysis involving four studies and more than 5,000 community-dwelling adults over the age of 60 years concluded that greater adherence to the Mediterranean diet was associated with a reduced risk of frailty.
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A Possible New Treatment for HTLV-1-associated Myelopathy
Mogamulizumab reduces central nervous system inflammation and improves spasticity in patients with HTLV-1-associated myelopathy.
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Parsonage-Turner Syndrome: Where’s the Lesion?
SYNOPSIS: This careful analysis of MRI imaging of the brachial plexus in patients with well-defined Parsonage-Turner Syndrome showed that the lesions are in peripheral branches of the brachial plexus and not in the roots or cords.
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Lessons Learned From a Failed Anti-amyloid Trial for Alzheimer’s Disease
Despite the disappointing results in EXPEDITION 3, modifications of clinical trials for Alzheimer’s disease (AD) should be undertaken and trials targeting preclinical or early AD should continue with anti-amyloid agents.
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Postpartum Headache May Be a Symptom of a Serious Problem
Consultation for acute postpartum headache resulted in the diagnosis of a secondary cause of headache in almost three out of four women, with almost half of the secondary headaches due to a hypertensive disorder of pregnancy or to cerebrovascular disease.
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Coprescription of Triptans and SSRI-type Medications and the Serotonin Syndrome
A recent study provided reassurance that the use of triptan antimigraine medications with selective serotonin reuptake inhibitor and selective norepinephrine reuptake inhibitor antidepressants is safe.
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Autoimmune Encephalitis: Not Rare and Increasing
Detection of autoimmune encephalitis is increasing over time. According to the results from this population-based study, its prevalence and incidence are comparable to infectious encephalitis.
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Infectious Disease Alert Updates
Online Sex and Sexually Transmitted Diseases; Swingers Come Out; HIV-positive Patients Require Hepatitis B Vaccine
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Adjuvanted Recombinant Hepatitis B Vaccine (Heplisav-B)
Heplisav-B is a new hepatitis B vaccine approved by the FDA in November 2017.