Browse Internal Medicine Articles by Topic

Combination Drug Therapy for Hypertension

A large regional database study from Italy demonstrated that initial combination therapy for newly diagnosed hypertension results in fewer major adverse cardiovascular events at one year compared to monotherapy.

Safety and Efficacy of HEART Score Use in the ED

A prospective observational study of 30-day outcomes in patients with suspected acute coronary syndromes triaged in EDs before and after the implementation of the HEART score showed that there were fewer hospitalizations and a very low risk of death or myocardial infarction among low-risk patients who were discharged without further cardiac testing.

An Update to the Management of Atrial Fibrillation

This focused update to the 2014 guidelines for the management of atrial fibrillation (AF) includes revisions to anticoagulation recommendations and the role of catheter ablation of AF in patients with heart failure.

Volume-Outcome Relationship With Newer-Generation TAVR Devices?

This large-scale retrospective analysis of all balloon-expandable transcatheter aortic valve replacement valves revealed no apparent relationship between procedure volume and outcomes after an initial learning curve of 200 procedures.

Rethinking the Prophylactic Use of Proton Pump Inhibitors in the ICU

The authors of this multicenter, blinded, randomized trial found that among critically ill adults at risk for gastrointestinal (GI) bleeding, fewer patients in the pantoprazole group exhibited clinically important GI bleeding compared to placebo, although mortality at 90 days was similar in both groups.

Late Awakening Among Cardiac Arrest Survivors Predicts Worse Short- and Long-Term Outcomes

In this retrospective single-center study, late awakening after cardiac arrest was associated with a higher rate of unfavorable outcomes immediately after awakening and at three months.

Mechanical Circulatory Support for Cardiogenic Shock

Exploring what options exist for temporary percutaneous mechanical support for cardiogenic shock associated with acute myocardial infarction?

Is There RBBB, Acute Ischemia, or Both?

The ECG in the figure was obtained from a 35-year-old man with a 20-year history of smoking. He presented to the ED with new-onset chest discomfort. He was hemodynamically stable at the time this tracing was obtained. How would one interpret his ECG? Is there right bundle branch block (RBBB)? Is there evidence of acute posterior ischemia or infarction?

Sarecycline Tablets (Seysara)

Sarecycline is indicated for the treatment of inflammatory lesions of non-nodular moderate to severe acne in patients 9 years of age and older.

Is Sanitizer Better Than Soap?

In day care settings, the implementation of hand hygiene programs reduced respiratory illness, absenteeism, and antibiotic use in children 0-3 years of age. Using hand sanitizer was more effective than washing with soap and water.