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The gold standard in the era of EBM is the randomized controlled trial (RCT). A properly designed and carried out RCT, in patients similar to those the practitioner manages and using end points relevant to both practitioner and patient, is more likely to be free from bias and to produce results that will stand up over time than other types of investigation such as retrospective analyses, case-control studies, and unsystematic clinical observations.
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Patients who received hyperoxia during general surgery had an increase in surgical site infections compared to those who received a lower oxygen concentration.
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The MATCH data provide quite strong evidence that the clopidogrel-aspirin combination is a less favorable option than previously thought, but its use may not be completely contraindicated.
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The means by which prions cause neuropathologic damage remains to be established.
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Soy as part of a healthy diet. Altern Med Alert 2004;7(Suppl 5):S1-S4.
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Greenfield RH. Acupuncture for chronic headache. Altern Med Alert 2004;7(5):58-59.
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Kiefer D. Goldenseal and the common cold: Is there any evidence? Altern Med Alert 2004;7(5):55-58.
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Greenfield RH. Stress and multiple sclerosis. Altern Med Alert 2004;7(5):59-60.