-
Institution of a daily pharmacist-enforced intervention designed to improve adherence to sedation guidelines decreased the duration of mechanical ventilation and ICU stay.
-
-
Elevated troponin i is a nonspecific finding, but suggests a poor prognosis regardless of its cause.
-
Ceftobiprole, a novel broad-spectrum cephalosporin with activity against MRSA, was non-inferior to vancomycin plus ceftazidime in a study of complicated skin and skin-structure infections. This is the first β-lactam with reliable activity against methicillin resistant Staphylococcus aureus (MRSA) to be evaluated in advanced-stage clinical trials.
-
Randomized studies of neuroprotective agents for ischemic stroke have resulted in a series of failures, as multiple agents, promising in animal models, have failed when applied to human subjects. By contrast, intracerebral hemorrhage (ICH) has been somewhat a "neglected stepsister" when compared to ischemic stroke; it has been studied minimally, despite its high morbidity and mortality.
-
The impact of 7-valent pneumococcal conjugate vaccine (PCV7) was studied using the Nationwide Inpatient Sample, which is the largest source of inpatient data in the United States and drawn from about 1000 community hospitals.
-
A retrospective, cohort study of 200 episodes randomly selected from 315 episodes, during 2000-2003, at Children's Hospital of Philadelphia, of laboratory-confirmed bloodstream infections among out-patient children with central venous catheters was performed to determine the optimum duration of antibiotic therapy before infection could be reliably excluded.
-
In this study, 100 consecutive patients, who were receiving several different cytotoxic chemotherapy regimens for a variety of cancers, were self-referred on the basis of perception of mucositis, elevated temperature at home, malaise, or were referred by a nurse based on assessment of potential infection or mucositis.
-
A blinded, prospective, case-control study of 40 children meeting all of the DSM-IV criteria for PANDAS matched with 40 children with obsessive-compulsive disorder and/or a chronic tic disorder was conducted with periodic intensive laboratory testing for group A streptococcus for 2 years, especially with clinical exacerbations or acute illness.
-
For this study, 279 patients from five groups (including 70 with proven or probable invasive pulmonary aspergillosis, 27 patients with blood cultures positive for a fungal pathogen, and 20 with PCP) were BG levels were measured with the Fungitell test kit.
