Internal Medicine
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Statins and Muscle Symptoms: Cause and Effect?
An analysis of three large simvastatin trials revealed muscle symptoms on simvastatin are common, but true myopathy is rare and can be predicted by evaluating certain risk factors for its development, which can help guide patient management.
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Is Effective Transcatheter Tricuspid Repair Becoming a Reality?
In two trials of transcatheter devices treating tricuspid regurgitation, the authors observed high efficacy and low adverse event rates.
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Why Is There Group Beating?
The ECG in the figure was obtained from a 40-year-old man with an irregular heartbeat. How would one interpret this rhythm?
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Relugolix Tablets (Orgovyx)
Relugolix should be prescribed to adults with advanced prostate cancer.
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Prophylactic PCI for Vulnerable Plaques
In this proof-of-concept trial, treatment of non-flow limiting vulnerable plaque by PCI with bioabsorbable stents resulted in no significant difference in lesion-related events compared with optimal medical therapy.
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Does MRSA Nares Colonization Predict Non-Respiratory MRSA Infections?
Nares screening for methicillin-resistant Staphylococcus aureus (MRSA) carried a high negative predictive value to rule out MRSA infections at various sites.
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Air Pollution and Cognitive Decline
In this large prospective cohort study of subjects in Manhattan, researchers demonstrated an association between exposure to air pollution and decline in cognitive function over time in one cohort, but not the other.
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Improve Diet to Put Out the GERD Fire
The authors estimated nearly 40% of gastroesophageal reflux disease symptoms that occur at least weekly can be prevented through a modification of lifestyle factors.
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Biden Administration Takes First Steps Against COVID-19
The new president signed a series of executive actions to accelerate nation’s pandemic response.
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Clinical and Genetic Characterizations to Diagnose Sarcoglycanopathies
Sarcoglycanopathies, caused by various genetic mutations, may cause limb-girdle forms of muscular dystrophy early in life. Although there are no specific treatments for these disorders at this time, the clinical and genetic characterizations will assist in more precise diagnosis that will be critical to develop new molecular-based therapies.