Internal Medicine Alert
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The Danger of ADHD Overdiagnosis
A growing concern about overdiagnosis of attention-deficit/hyperactivity disorder in adolescents and children demonstrates a need for a decisive answer to this concern. -
Importance of Atherosclerotic Disease Risk Factors in Myocardial Infarction Patients
ST-elevation myocardial infarction patients without standard risk factors recorded a higher all-cause mortality rate that was particularly evident in women. Using proper therapy in these patients may attenuate this risk. -
Antibiotic Therapy: How Long Is Long Enough?
The CDC and the American College of Physicians have provided advice on the best practice regarding the duration of antibiotic therapy for several common infections. -
Giving the Cold Shoulder to Drug Therapy for Atrial Fibrillation
In two randomized trials published simultaneously, cryoballoon ablation proved superior to drug therapy for prevention of arrhythmia recurrence in patients with paroxysmal atrial fibrillation.
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What Is the Rhythm? What Is the Culprit Artery?
The ECG in the figure was obtained from a middle-aged man with chest pain. What can one say about the cardiac rhythm? How can one determine the “culprit” artery?
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Viloxazine Extended-Release Capsules (Qelbree)
Viloxazine should be prescribed to treat ADHD in patients age 6 to 17 years.
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Intracranial Plaque Rupture and Stroke
An MRI study of cerebral circulation in patients with embolic stroke of undetermined etiology showed evidence of atherosclerotic plaque in most patients.
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Dasiglucagon Injection (Zegalogue)
Dasiglucagon should be prescribed to treat severe hypoglycemia in pediatric and adult patients (≥ age 6 years).
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Antibiotics: Less Is Better, Sometimes
In England, and likely in many other areas of the world, antibiotics are given for longer than necessary. Excessively long durations of antibiotic use do not help patients and risk leading to more resistant infections.
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Is Empagliflozin Safe in Combination with a Neprilysin Inhibitor for Heart Failure?
A prespecified subgroup analysis of heart failure patients with reduced ejection fraction who were on neprilysin inhibitors before empagliflozin was administered (vs. those not on neprilysin inhibitors) showed the reduction in mortality and hospital admissions for heart failure was not attenuated by concurrent neprilysin use.