Treatment of acute lymphoblastic leukemia in elderly patients remains problematic. Recent data suggests imatinib with chemotherapy is both effective and well-tolerated in elderly patients with Philadelphia chromosome-positive ALL.
Neuraminidase inhibitors are a class of antivirals that have activity against both influenza A and B viruses. Influenza neuraminidase cleaves terminal sialic acid residues and damages the receptors recognized by viral hemagglutinin, thereby facilitating release of virus from infected cells. In the presence of a neuraminidase inhibitor, release of virus from infected cells is impaired and the progeny viruses that are freed clump together, as sialic acid has not been cleaved.
Dietary Phytoestrogens and Lung Cancer Risk; Effectiveness of Influenza Vaccine in the Elderly; Why Does Tadalafil Cause Back Pain?
