Infectious Disease
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Surge of HIV Patients Present to EDs, Leaders Call for Expanded Screening
Investigators discovered a more than twofold increase in cases of acute HIV during the COVID-19 pandemic as part of an ED-based screening program at UChicago Medicine. The cause of the increase remains unknown, but it underscores the importance of screening despite the fact the pandemic has strained all resources.
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EDs Administer Monoclonal Antibody Therapy to High-Risk COVID-19 Patients
Clinicians can use new monoclonal antibody therapies to treat high-risk patients presenting with mild to moderate COVID-19 symptoms. However, despite the promise to depress viral loads, logistical and other challenges continue to stand in the way of larger-scale use. Still, some EDs are trying the therapeutics, with promising results.
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Acute Myocardial Infarction, or Related to COVID-19?
The ECG in the figure was obtained from a man in his 30s. How would one interpret this tracing if told the patient’s only symptom was recent shortness of breath on exertion that he had not experienced?
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Vericiguat Tablets (Verquvo)
Vericiguat is indicated to lower the risk of cardiovascular death and heart failure hospitalization in adults with symptomatic chronic heart failure and an ejection fraction less than 45%.
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Is There an Ideal Time to Administer Antihypertension Medications?
Taking all antihypertensive agents before bed vs. upon awakening in hypertensive patients showed there was less hypertension during sleep and few cardiovascular events over a six-year follow-up.
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Time-Restricted Eating, Weight Loss, and Metabolism
A randomized clinical trial comparing time-restricted eating with a 16-hour fasting interval to a structured three-meal-per-day control group resulted in equivalent weight loss in both groups and no reduction in metabolic markers in either group.
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Healthy or Not: The Controversy Over Egg Consumption Continues
A large meta-analysis showed higher consumption of eggs (eating more than one egg daily) was not associated with an increased risk of cardiovascular disease, and was associated with a lower risk of coronary artery disease.
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COVID-19 Affected U.S. Life Expectancy: How Bad Is It?
The pandemic dinged the average, but the latest data do not tell the whole story.
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One Dose, Lower Temps May Suffice for Pfizer/BioNTech COVID-19 Vaccine
Encouraging new data emerge regarding storage, administration requirements.
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U.K. Approves First COVID-19 Human Challenge Trial
Volunteers will be infected with virus so researchers can learn more about pathology, speed effective vaccine development.